Tussionex

Tussionex (chlorpheniramine and hydrocodone) is a combination antihistamine/antitussive drug prescribed for symptomatically managing cold and allergy symptoms. Common side effects of Tussionex include:

• lightheadedness,
• dizziness,
• drowsiness,
• trouble concentrating,
• mood changes,
• anxiety,
• blurred vision,
• constipation,
• nausea,
• vomiting,
• loss of appetite,
• dry mouth or throat,
• sweating,
• itching or skin rash, and
• disturbed coordination.

Contact your doctor if you have serious side effects of Tussionex including:

• shallow breathing,
• chest tightness,
• painful or difficult urination,
• mental/mood changes (such as depression, agitation, confusion, hallucinations),
• stomach/abdominal pain,
• fast/slow/irregular heartbeat, or
• unusual behavior.

Tussionex usual dose is 5 ml twice a day. Tussionex may interact with other drugs that can cause sleepiness (narcotics, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety), any other cold or allergy medicines, atropine, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, glycopyrrolate, mepenzolate, bladder or urinary medications, irritable bowel medications, or MAO inhibitors. Tell your doctor all medications and supplements you use. Tussionex should not be used during pregnancy as it may cause adverse effects in the fetus unless the potential benefit outweighs the potential unknown risk to the fetus. Tussionex is secreted in human breast milk and may cause adverse effects in the new born. Consult your doctor before breastfeeding.

Our Tussionex Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

 

Tussionex Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medications, hydrocodone can slow your breathing. Death may occur if breathing becomes too weak.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Stop using this medicine and call your doctor at once if you have:

• severe drowsiness;
• noisy breathing, sighing, shallow breathing;
• severe constipation;
• a light-headed feeling, like you might pass out;
• a slow heart rate or weak pulse;
• confusion; or
• adrenal gland problems--nausea, vomiting, loss of appetite, dizziness, feeling weak or tired.

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

Common side effects may include:

• trouble breathing;
• drowsiness;
• confusion;
• nausea, vomiting; or
• little or no urination.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Tussionex (Hydrocodone and Chlorpheniramine)

 

Tussionex Professional Information

SIDE EFFECTS

Gastrointestinal Disorders

Nausea and vomiting may occur; they are more frequent in ambulatory than in recumbent patients. Prolonged administration of TUSSIONEX Pennkinetic Extended-Release Suspension may produce constipation.

General Disorders And Administration Site Conditions

Death

Nervous System Disorders

Sedation, drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, euphoria, dizziness, psychic dependence, mood changes.

Renal And Urinary Disorders

Ureteral spasm, spasm of vesical sphincters, and urinary retention have been reported with opiates.

Respiratory, Thoracic And Mediastinal Disorders

Dryness of the pharynx, occasional tightness of the chest, and respiratory depression (see CONTRAINDICATIONS).

TUSSIONEX Pennkinetic Extended-Release Suspension may produce dose-related respiratory depression by acting directly on brain stem respiratory centers (see OVERDOSE). Use of TUSSIONEX Pennkinetic Extended-Release Suspension in children less than 6 years of age has been associated with fatal respiratory depression. Overdose with TUSSIONEX Pennkinetic Extended- Release Suspension in children 6 years of age and older, in adolescents, and in adults has been associated with fatal respiratory depression.

Skin And Subcutaneous Tissue Disorders

Rash, pruritus.

Read the entire FDA prescribing information for Tussionex (Hydrocodone and Chlorpheniramine)