Squamous cell carcinoma antigen (SCC)
Squamous cell carcinoma antigen (SCC)
The indications for squamous cell carcinoma antigen (SCC) - monitoring course and therapy of squamous cell carcinoma of the cervix, nasopharynx, ear, lungs and esophagus. Squamous cell carcinoma antigen is a glycoprotein with a molecular weight of 42 kDa, isolated from liver metastases of squamous cell carcinoma of the cervix.
Limit of normal antigen squamous cell carcinomais not higher than 2 ng/ml.
Elevated levels of squamous cell carcinoma antigenis diagnosed in patients with squamous cell carcinoma of the cervix (85%), in carcinoma of the nasopharynx and ear (60%). Increased levels of squamous cell carcinoma antigen are found in renal failure (up to 10 ng/ml), sometimes patients with hepatobiliary pathology.
In the study of this marker you should pay attention to the material and work with the test samples, as contamination by elements of the skin and saliva leads to false-positive results.
Elevated levels of squamous cell carcinoma antigen detected in 31% of cases of squamous cell lung carcinoma, and in 17% of cases of lung cancer.
See also
- Complete blood count (CBC):
- Urinalysis:
- Cerebrospinal fluid (CSF) analysis
- Biochemical markers of bone remodeling and diseases
- Markers of autoimmune connective tissue diseases (CTDs)
- Antiphospholipid syndrome (APS)
- Lipoprotein(a), Lp(a)
- Semen analysis (sperm count test)
- Tumor markers tests (cancer biomarkers):
- β-2 microglobulin (beta-2)
- Alpha-fetoprotein (AFP)
- Squamous cell carcinoma antigen (SCC)
- S100 protein tumormarker
- Calcitonin
- Mucin-like carcinoma-associated antigen (MCA)
- Neuron-specific enolase (NSE)
- Prostate-specific antigen (PSA) test
- Cancer associated antigen 549 (CA 549)
- CA 19-9, CA 72-4, CA 50, CA 15-3 and CA 125 tumor markers (cancer antigens)
- Carcinoembryonic antigen (CEA)
- Thyroglobulin (Tg)
- Tissue polypeptide antigens (ТРА, TPS)
- Cytokeratin-19 fragment (CYFRA 21-1)
- Human chorionic gonadotrophin (hCG)
