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Xeljanz Side Effects Center

Medically reviewed by Min Clinic Staff | Updated: January 2026

Xeljanz (Tofacitinib Tablets) side effects drug center

 

PROFESSIONAL

CONSUMER

SIDE EFFECTS

 

Xeljanz Side Effects Center

What Is Xeljanz?

Xeljanz (tofacitinib citrate) is a Janus kinase (JAK) inhibitor used to treat adults with moderate to severely active rheumatoid arthritis (RA) who have not responded well to methotrexate, or cannot tolerate it.

What Are Side Effects of Xeljanz?

Common side effects of Xeljanz are:

  • upper respiratory tract infections,
  • headache,
  • diarrhea, and
  • cold symptoms such as sore throat, runny or stuffy nose.

Tell your doctor if you experience serious side effects of Xeljanz including:

  • feeling very tired,
  • yellow skin or eyes (jaundice),