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MetroGel vs. Soolantra

Are MetroGel and Soolantra the Same Thing?

MetroGel (metronidazole) and Soolantra (ivermectin) cream are topical (for the skin) preparations used to treat skin lesions caused by rosacea.

MetroGel and Soolantra belong to different drug classes. MetroGel is an antibiotic and Soolantra is a macrocyclic lactone anthelmintic.

Side effects of MetroGel and Soolantra that are similar include application site reactions (skin stinging, burning, irritation, dryness, redness, scaling).

Side effects of MetroGel that are different from Soolantra include metallic taste in mouth, nausea, headache, numbness or tingly feeling in your hands or feet, cough, stuffy nose, sore throat, cold symptoms, or vaginal itching or discharge.

Side effects of Soolantra that are different from MetroGel include eye irritation or red eyes.

MetroGel may interact with blood thinners.

Soolantra may interact with other drugs.

What Are Possible Side Effects of MetroGel?

Common side effects of MetroGel include:

  • skin stinging/burning/irritation/dryness/ redness/scaling/itching,
  • metallic taste,
  • nausea,
  • headache,
  • numbness or tingly feeling in your hands or feet,
  • cough,
  • stuffy nose,
  • sore throat,
  • cold symptoms, or
  • vaginal itching or discharge.

What Are Possible Side Effects of Soolantra?

Common side effects of Soolantra include:

  • skin burning or stinging sensation and skin irritation where the medicine is applied,
  • dry skin,
  • eye irritation, or
  • red eyes.

What Is MetroGel?

MetroGel (metronidazole) Topical gel is a topical (for the skin) antibiotic used to treat skin lesions caused by rosacea. MetroGel is available in generic form.

What Is Soolantra?

Soolantra (ivermectin) cream is a macrocyclic lactone anthelmintic used to treat inflammatory lesions of rosacea.

What Drugs Interact With MetroGel?

Metrogel may interact with blood thinners such as warfarin (Coumadin). It is not likely that other drugs you take orally or inject will have an effect on topically applied Metrogel. Tell your doctor all medications and supplements you use. Metrogel should be used only when prescribed during pregnancy. Metrogel passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Soolantra?

Tell your doctor all medications and supplements you use. During pregnancy, Soolantra should only be used if prescribed. This drug passes into breast milk when taken orally. It is unknown if it passes into breast milk when applied topically. Consult your doctor before breastfeeding.

How Should MetroGel Be Taken?

Apply and rub in a thin film dose of Metrogel once daily to affected area(s).

How Should Soolantra Be Taken?

Apply a dose of Soolantra to the affected areas of the face once daily. Use a pea-size amount for each area of the face (forehead, chin, nose, each cheek) that is affected. Spread as a thin layer, avoiding the eyes and lips. Soolantra may interact with other drugs.

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