Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Topical
Medically reviewed by Min Clinic Staff | Updated: January 2026
Topical: Pertaining to a particular surface area. For example, a topical agent is applied to a certain area of the skin and is intended to affect only the area to which it is applied. Whether its effects are indeed limited to that area depends on whether the agent stays where it is put or is absorbed into the bloodstream. Cortisone creams are topical 'medications.