Brintellix (Trintellix) vs. Effexor

• Are Brintellix (Trintellix) and Effexor the Same Thing?
• What Are Possible Side Effects of Brintellix (Trintellix)?
• What Are Possible Side Effects of Effexor?
• What Is Brintellix (Trintellix)?
• What Is Effexor?
• What Drugs Interact with Brintellix (Trintellix)?
• What Drugs Interact with Effexor?
• How Should Brintellix (Trintellix) Be Taken?
• How Should Effexor Be Taken?

Brintellix (Trintellix) (vortioxetine) and Effexor (venlafaxine) are antidepressants used to treat major depressive disorder (MDD).

The brand name Brintellix (Trintellix) was changed to Trintellix in June 2016 because of confusion with the name of an antiplatelet drug called Brilinta (ticagrelor).

Common side effects of Brintellix (Trintellix) include:

• nausea,
• diarrhea,
• constipation,
• vomiting,
• sexual dysfunction,
• dry mouth,
• gas,
• dizziness,
• abnormal dreams, and
• itching.

Common side effects of Effexor include:

• dizziness,
• nervousness,
• nausea,
• constipation,
• headaches,
• anxiety,
• insomnia,
• strange dreams,
• drowsiness,
• increased sweating,
• blurred vision,
• dry mouth,
• changes in appetite or weight,
• decreased sex drive,
• impotence,
• difficulty having an orgasm,
• increased blood pressure, and
• seizures.

Brintellix (vortioxetine) is an antidepressant used to treat major depressive disorder (MDD).

Effexor is a prescription medicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of not treating it. You should discuss all treatment choices with your healthcare provider. Talk to your healthcare provider if you do not think that your condition is getting better with Effexor.

Brintellix may interact with monoamine oxidase inhibitors (MAOIs), SSRIs, SNRIs, triptans, buspirone, tramadol, tryptophan, bupropion, fluoxetine, paroxetine, quinidine, rifampicin, carbamazepine, or phenytoin. Tell your doctor all medications and supplements you use. Tell your doctor if you become pregnant or intend to become pregnant during therapy with Brintellix.

Before starting Effexor, USP, tell your healthcare provider if you:

• Are taking certain drugs such as:
• Medicines used to treat migraine headaches such as:
• triptans
• Medicines used to treat mood, anxiety, psychotic or thought disorders, such as:
• tricyclic antidepressants
• lithium
• SSRIs
• SNRIs
• antipsychotic drugs
• Medicines used to treat pain such as:
• tramadol
• Medicines used to thin your blood such as:
• warfarin
• Medicines used to treat heartburn such as:
  • Cimetidine
• Over-the-counter medicines or supplements such as:
• Aspirin or other NSAIDs
• Tryptophan
• St. John's Wort
• have heart problems
• have diabetes
• have liver problems
• have kidney problems
• have thyroid problems
• have glaucoma
• have or had seizures or convulsions
• have bipolar disorder or mania
• have low sodium levels in your blood
• have high blood pressure
• have high cholesterol
• have or had bleeding problems
• are pregnant or plan to become pregnant. It is not known if Effexor, USP will harm your unborn baby. Talk to your healthcare provider about the benefits and risks of treating depression during pregnancy
• are breast-feeding or plan to breast-feed. Some Effexor, USP may pass into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking Effexor, USP.

The recommended starting dose of Brintellix is 10 mg taken orally once daily.

• Take venlafaxine tablets, USP exactly as prescribed. Your healthcare provider may need to change the dose of venlafaxine tablets, USP until it is the right dose for you.
• Venlafaxine tablets, USP is to be taken with food.
• If you miss a dose of venlafaxine tablets, USP, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of venlafaxine tablets, USP at the same time.
• If you take too much venlafaxine tablets, USP, call your healthcare provider or poison control center right away, or get emergency treatment.
• When switching from another antidepressant to venlafaxine tablets, USP your doctor may want to lower the dose of the initial antidepressant first to avoid side effects