Vanos

Vanos (fluocinonide) Cream, 0.1%, is a topical (for the skin) steroid used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Common side effects of Vanos Cream include burning, stinging, itching, dryness, peeling, or redness when Vanos Cream is first applied to the skin. These side effects should disappear in a few days as your body adjusts to Vanos Cream. Other side effects of Vanos Cream include headache, stuffy nose, sore throat, thinning or softening of your skin, skin rash or irritation around your mouth, swollen hair follicles, changes in color of treated skin, blisters, pimples, crusting of treated skin, or stretch marks.

For psoriasis, apply a thin layer dose of Vanos Cream once or twice daily to the affected skin areas as directed by a physician. For atopic dermatitis, apply a thin layer of Vanos Cream once daily to the affected skin areas as directed by a physician. For corticosteroid responsive dermatoses, other than psoriasis or atopic dermatitis, apply a thin layer of Vanos Cream once or twice daily to the affected areas as directed by a physician. It is not likely that other drugs you take orally or inject will have an effect on topically applied Vanos. But many drugs can interact with each other. Tell your doctor all prescription and over-the-counter medications and supplements you use. During pregnancy, Vanos should be used only when prescribed. It is unknown if this drug passes into breast milk when applied to the skin. Similar medications pass into breast milk when taken by mouth. Consult your doctor before breastfeeding.

Our Vanos (fluocinonide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

 

Vanos Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• worsening of your skin condition; or
• possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Steroid medicine can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects may include:

• burning, stinging, itching, or dryness of treated skin;
• redness or crusting around your hair follicles;
• stretch marks;
• spider veins;
• acne;
• lightened color of treated skin;
• headache; or
• stuffy nose, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Vanos (Fluocinonide)

 

Vanos Professional Information

SIDE EFFECTS

Clinical Trials Experience

Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice.

In clinical trials, a total of 443 adult subjects with atopic dermatitis or plaque-type psoriasis were treated once daily or twice daily with VANOS Cream for 2 weeks. The most commonly observed adverse reactions in these clinical trials were as follows:

Table 1: Most Commonly Observed Adverse Reactions ( ≥ 1%) in Adult Clinical Trials

Adverse Reaction	VANOS Cream, once daily (n=216)	VANOS Cream, twice daily (n=227)	Vehicle Cream, once or twice daily (n=211)
Headache	8 (3.7%)	9 (4.0%)	6(2.8%)
Application Site Burning	5 (2.3%)	4 (1.8%)	14 (6.6%)
Nasopharyngitis	2 (0.9%)	3 (1.3%)	3 (1.4%)
Nasal Congestion	3 (1.4%)	1 (0.4%)	0

Safety in patients 12 to 17 years of age was similar to that observed in adults.

Postmarking Experience

The following adverse reactions have been identified during post approval use of VANOS Cream:

Administration Site Conditions: discoloration, erythema, irritation, pruritus, swelling, pain and condition aggravated.

Immune System Disorders: hypersensitivity.

Nervous System Disorders: headache and dizziness.

Skin and Subcutaneous Tissue Disorders: acne, dry skin, rash, skin exfoliation and skin tightness.

Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Read the entire FDA prescribing information for Vanos (Fluocinonide)