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Sinequan

  • Generic Name: doxepin
  • Brand Name: Sinequan

side effects drug center sinequan (doxepin) drug - patient side effects and images

 

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CONSUMER

SIDE EFFECTS

Sinequan Patient Information Including Side Effects

Brand Names: Adapin, SINEquan

Generic Name: doxepin (capsules, oral concentrate)

What is doxepin (Adapin, SINEquan)?

Doxepin is a tricyclic antidepressant.

Doxepin capsules and oral concentrate (liquid) are used to treat symptoms of depression and/or anxiety associated with alcoholism, manic depression, or other mental illness.

Doxepin tablets (Silenor) are used to treat insomnia in people who have trouble staying asleep.

This medication guide provides only information about doxepin capsules and liquid.

Doxepin may also be used for purposes not listed in this medication guide.

What are the possible side effects of doxepin (Adapin, SINEquan)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

Common side effects may include:

  • drowsiness, dizziness;
  • increased blood pressure;
  • vision changes;
  • rash, swelling;
  • nausea, vomiting, indigestion;
  • little or no urination;
  • dry mouth, constipation; or
  • decreased or increased sex drive.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about doxepin (Adapin, SINEquan)?

You should not take doxepin if you have glaucoma or problems with urination.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

Sinequan Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking doxepin (Adapin, SINEquan)?

You should not use doxepin capsules or liquid if you are allergic to doxepin or similar medicines such as amoxapine or loxapine, or if you have:

  • glaucoma; or
  • urination problems.

Do not use doxepin if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

Tell your doctor if you have ever had:

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Doxepin is not approved for use by anyone younger than 12 years old.

How should I take doxepin (Adapin, SINEquan)?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Mix the measured dose with 4 ounces of water, milk, orange juice, grapefruit juice, tomato juice, prune juice, or pineapple juice. Do not mix with grape juice or a carbonated soft drink. Stir the mixture and drink all of it right away. Do not save it for later use.

Do not stop using doxepin suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

It may take up to 3 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Sinequan Patient Information including If I Miss a Dose

What happens if I miss a dose (Adapin, SINEquan)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose (Adapin, SINEquan)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of doxepin can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.

What should I avoid while taking doxepin (Adapin, SINEquan)?

Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

What other drugs will affect doxepin (Adapin, SINEquan)?

Using doxepin with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may affect doxepin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information (Adapin, SINEquan)?

Your pharmacist can provide more information about doxepin (capsules, oral concentrate).

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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