Neosporin-GU

What Is Neosporin G.U.?

Neosporin G.U. (neomycin sulfate–polymyxin B sulfate solution for irrigation) is a concentrated sterile antibiotic solution to be diluted for urinary bladder irrigation indicated for short-term use (up to 10 days) as a continuous irrigant or rinse in the urinary bladder of abacteriuric patients to help prevent bacteriuria and gram-negative rod septicemia associated with the use of indwelling catheters. Neosporin G.U. is available in generic form.

What Are Side Effects of Neosporin G.U.?

Common side effects of Neosporin G.U. include skin sensitization when applied topically, however, topical application to mucus membranes rarely results in local or systemic hypersensitivity reactions. Irritation of the urinary bladder mucosa may occur.

Dosage for Neosporin G.U.

For most patients, the inflow rate of the 1,000-mL saline solution of Neosporin G.U. should be adjusted to a slow drip to deliver about 1,000 mL every 24 hours. If the patient's urine output exceeds 2 liters per day, it is recommended that the inflow rate be adjusted to deliver 2,000 mL of the solution in a 24-hour period.

What Drugs, Substances, or Supplements Interact with Neosporin G.U.?

Neosporin G.U. may interact with other drugs. Tell your doctor all medications and supplements you use.

Neosporin G.U. During Pregnancy or Breastfeeding

Neosporin G.U. is not recommended for use during pregnancy; it may harm a fetus. Consult your doctor before breastfeeding.

Additional Information

Our Neosporin G.U. (neomycin sulfate–polymyxin B sulfate solution for irrigation) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.