Inderal XL
- Generic Name: inderal xl propranolol hydrochloride capsules
- Brand Name: Inderal XL
Inderal XL(Inderal XL Propranolol Hydrochloride Capsules) side effects drug center
Inderal XL Side Effects Center
Inderal XL (propranolol hydrochloride) extended-release capsules is a beta adrenergic blocker indicated for the treatment of high blood pressure (hypertension), to lower blood pressure. Common side effects of Inderal XL include fatigue, dizziness, and constipation.
The starting dose of Inderal XL is 80 mg, adjusted up to 120 mg if needed. Inderal XL may interact with warfarin, propafenone, bupropion, fluoxetine, paroxetine, quinidine, ciprofloxacin, enoxamine, fluvoxamine, fluconazole, fluvoxamine, ticlopidine, phenytoin, montelukast, smoking, rifampin, cholestyramine or colestipol, clonidine, alpha-blockers, dobutamine, MAO inhibitors or tricyclic antidepressants, and nonsteroidal anti-inflammatory drugs (NSAIDS). Tell your doctor all medications and supplements you use. During pregnancy, Inderal XL should be used only if prescribed. It is unknown if it could affect a fetus. Inderal XL passes into breast milk. Consult your doctor before breastfeeding.
Our Inderal XL (propranolol hydrochloride) extended-release capsules Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
Inderal XL Consumer Information
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- slow or uneven heartbeats;
- a light-headed feeling, like you might pass out;
- wheezing or trouble breathing;
- shortness of breath (even with mild exertion), swelling, rapid weight gain;
- sudden weakness, vision problems, or loss of coordination (especially in a child with hemangioma that affects the face or head);
- cold feeling in your hands and feet;
- depression, confusion, hallucinations;
- liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- low blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery;
- low blood sugar in a baby--pale skin, blue or purple skin, sweating, fussiness, crying, not wanting to eat, feeling cold, drowsiness, weak or shallow breathing (breathing may stop for short periods), seizure (convulsions), or loss of consciousness; or
- severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
- nausea, vomiting, diarrhea, constipation, stomach cramps;
- decreased sex drive, impotence, or difficulty having an orgasm;
- sleep problems (insomnia); or
- tired feeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Inderal XL (Inderal XL Propranolol Hydrochloride Capsules)
Inderal XL Professional Information
SIDE EFFECTS
Clinical Trials Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
Adverse reactions occurring at a rate of ≥ 3%, excluding those reported more commonly in placebo, encountered in the INDERAL XL placebo-controlled hypertension trials and plausibly related to treatment are shown in Table 1.
Table 1: Treatment-Emergent Adverse Reactions Reported
In ≥ 3% of Subjects
| Body System | Placebo (N=88) |
INDERAL XL | |
| 80 mg (N=89) |
120 mg (N=85) |
||
| Fatigue | 3 (3%) | 4 (5%) | 6 (7%) |
| Dizziness (except vertigo) | 2 (2%) | 6 (7%) | 3 (4%) |
| Constipation | 0 | 3 (3%) | 1(1%) |
Postmarketing Experience
In addition to adverse reactions reported from clinical trials, the following reactions have been identified during post-marketing use of INDERAL XL. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
The following adverse reactions were observed and have been reported with use of formulations of sustained- or immediate-release propranolol.
Allergic: Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions; pharyngitis and agranulocytosis; erythematous rash, fever combined with aching and sore throat, laryngospasm, and respiratory distress.
Autoimmune: Systemic lupus erythematosus (SLE).
Cardiovascular: exacerbation of peripheral arterial disease, arterial insufficiency, usually of the Raynaud type.
Central Nervous System: Light-headedness, mental depression, insomnia, lassitude, weakness, fatigue, visual disturbances, hallucinations, vivid dreams, short-term memory loss, emotional lability, slightly clouded sensorium, paresthesia of hands.
Gastrointestinal: Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, mesenteric arterial thrombosis, ischemic colitis.
Genitourinary: Male impotence; Peyronie's disease.
Hematologic: Agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura.
Musculoskeletal: Myopathy, myotonia.
Skin and mucous membranes: Stevens-Johnson syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasisiform rashes.
Read the entire FDA prescribing information for Inderal XL (Inderal XL Propranolol Hydrochloride Capsules)
&Copy; Inderal XL Patient Information is supplied by Cerner Multum, Inc. and Inderal XL Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.