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Fosamax Plus D Side Effects Center
Medically reviewed by Min Clinic Staff | Updated: January 2026
- Generic Name: alendronate sodium and cholecalciferol
- Brand Name: Fosamax Plus D
Fosamax Plus D(Alendronate Sodium and Cholecalciferol) side effects drug center
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Fosamax Plus D Side Effects Center
What Is Fosamax Plus D?
Fosamax Plus D (alendronate sodium & cholecalciferol) is a combination of a bisphosphonate and a form of vitamin D used to treat and prevent osteoporosis.
What Are Side Effects of Fosamax Plus D?
Common side effects of Fosamax Plus D include:
- stomach pain or upset,
- heartburn,
- constipation,
- diarrhea,
- gas,
- nausea,
- joint or back pain, or
- headache.
Tell your doctor if you have serious side effects of Fosamax Plus D including:

