Dynacin
- Generic Name: minocycline hydrochloride tablets
- Brand Name: Dynacin
- Drug Class: Tetracyclines
Dynacin (Minocycline Hydrochloride Tablets) side effects drug center
- Related Drugs
- fever,
- loss of appetite,
- nausea,
- vomiting,
- diarrhea,
- indigestion/heartburn,
- inflammation of the mouth, lips, and/or tongue,
- difficulty swallowing,
- underdeveloped tooth enamel/tooth discoloration,
- vaginal inflammation or infection,
- liver problems,
- kidney problems,
- hair loss,
- itching,
- red bumps on skin,
- nail discoloration,
- rash,
- sensitivity of skin to sunlight,
- cough,
- shortness of breath,
- joint pain and swelling,
- hives,
- allergic reactions,
- dizziness,
- drowsiness,
- spinning sensation (vertigo), and
- ringing in the ears
- anticoagulants,
- penicillin,
- antacids containing aluminum, calcium, or magnesium, and iron-containing preparations,
- methoxyflurane,
- oral contraceptives,
- isotretinoin, and
- ergot alkaloids or their derivatives
- bronchospasm (wheezing, chest tightness, trouble breathing);
- a seizure;
- kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath;
- low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;
- increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, vision problems, pain behind your eyes; or
- signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, loss of appetite, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes).
- numbness, tingling, burning pain;
- hair loss;
- discoloration of you skin or nails.
- dizziness, spinning sensation;
- muscle or joint pain;
- nausea, diarrhea, loss of appetite;
- swollen tongue, cough, trouble swallowing;
- rash, itching; or
- headache.
What Is Dynacin?
Dynacin (minocycline hydrochloride tablet) is a tetracycline antibiotic used to treat a wide variety of infections due to susceptible strains of microorganisms such as Rickettsiae, Mycoplasma pneumoniae, Chlamydia trachomatis, Chlamydia psittaci, Ureaplasma urealyticum, Borrelia recurrentis, Haemophilus ducreyi, Yersinia pestis, Francisella tularensis, Vibrio cholerae, Campylobacter fetus, Brucella species, Bartonella bacilliformis, Calymmatobacterium granulomatis, Escherichia coli, Enterobacter aerogenes, Shigella species, Acinetobacter species, Haemophilus influenzae, Kiebsiella species, Streptococcus pneumoniae, Staphylococcus aureus, Neisseria gonorrhoeae, Treponema pallidum, Listeria monocytogenes, Bacillus anthracis, Fusobacterium fusiforme, Actinomyces israelii, and Clostridium species.
What Are Side Effects of Dynacin?
Side effects of Dynacin include:
Dosage for Dynacin
The usual adult dosage of Dynacin tablets is 200 mg initially followed by 100 mg every 12 hours. Alternatively, if more frequent doses are preferred, two or four 50 mg Dynacin tablets may be given initially followed by one 50 mg tablet four times daily. The usual pediatric dose of Dynacin is 4 mg/kg initially followed by 2 mg/kg every 12 hours, not to exceed the usual adult dose.
Dynacin In Children
Dynacin is not recommended for use in children below 8 years of age unless the expected benefits of therapy outweigh the risks.
What Drugs, Substances, or Supplements Interact with Dynacin?
Dynacin may interact with other medicines such as:
Tell your doctor all medications and supplements you use.
Dynacin During Pregnancy and Breastfeeding
Tell your doctor if you are pregnant or plan to become pregnant before using Dynacin; it may harm a fetus. Tetracyclines such as Dynacin pass into breast milk. Breastfeeding while using Dynacin is not recommended because of the potential for serious adverse reactions in nursing infants.
Additional Information
Our Dynacin (minocycline hydrochloride tablet) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, fever, swollen glands, joint pain, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Dynacin (Minocycline Hydrochloride Tablets)
SIDE EFFECTS
Due to oral minocycline's virtually complete absorption, side effects to the lower bowel, particularly diarrhea, have been infrequent. The following adverse reactions have been observed in patients receiving tetracyclines.
Body as a whole: Fever, and discoloration of secretions.
Gastrointestinal: Anorexia, nausea, vomiting, diarrhea, dyspepsia, stomatitis, glossitis, dysphagia, enamel hypoplasia, enterocolitis, pseudomembranous colitis, pancreatitis, inflammatory lesions (with monilial overgrowth) in the oral and anogenital regions. Instances of esophagitis and esophageal ulcerations have been reported in patients taking the tetracycline-class antibiotics in capsule and tablet form. Most of these patients took the medication immediately before going to bed (see DOSAGE AND ADMINISTRATION).
Genitourinary: Vulvovaginitis.
Hepatic toxicity: Hyperbilirubinemia, hepatic cholestasis, increases in liver enzymes, fatal hepatic failure, and jaundice. Hepatitis, including autoimmune hepatitis, and liver failure have been reported (see PRECAUTIONS).
Skin: Alopecia, erythema nodosum, hyperpigmentation of nails, pruritus, toxic epidermal necrolysis, and vasculitis. Maculopapular and erythematous rashes. Exfoliative dermatitis has been reported. Fixed drug eruptions have been reported. Lesions occurring on the glans penis have caused balanitis. Erythema multiforme and Stevens-Johnson syndrome have been reported. Photosensitivity is discussed above (see WARNINGS). Pigmentation of the skin and mucous membranes has been reported.
Respiratory: Cough, dyspnea, bronchospasm, exacerbation of asthma, and pneumonitis.
Renal toxicity: Interstitial nephritis. Elevations in BUN have been reported and are apparently dose related (see WARNINGS). Reversible acute renal failure has been reported.
Musculoskeletal: Arthralgia, arthritis, bone discoloration, myalgia, joint stiffness, and joint swelling.
Hypersensitivity reactions: Urticaria, angioneurotic edema, polyarthralgia, anaphylaxis/anaphylactoid reaction (including shock and fatalities), anaphylactoid purpura, myocarditis, pericarditis, exacerbation of systemic lupus erythematosus and pulmonary infiltrates with eosinophilia have been reported. A transient lupus-like syndrome and serum sickness-like reactions also have been reported.
Blood: Agranulocytosis, hemolytic anemia, thrombocytopenia, leukopenia, neutropenia, pancytopenia, and eosinophilia have been reported.
Central Nervous System: Convulsions, dizziness, hypesthesia, paresthesia, sedation, and vertigo. Bulging fontanels in infants and benign intracranial hypertension (pseudotumor cerebri) in adults have been reported (see PRECAUTIONS-General). Headache has also been reported.
Other: Thyroid cancer has been reported in the post-marketing setting in association with minocycline products. When minocycline therapy is given over prolonged periods, monitoring for signs of thyroid cancer should be considered. When given over prolonged periods, tetracyclines have been reported to produce brown-black microscopic discoloration of the thyroid gland. Cases of abnormal thyroid function have been reported.
Tooth discoloration in children less than 8 years of age, and also in adults, has been reported (see WARNINGS).
Oral cavity discoloration (including tongue, lip, and gum) have been reported.
Tinnitus and decreased hearing have been reported in patients on minocycline hydrochloride.
The following syndromes have been reported. In some cases involving these syndromes, death has been reported. As with other serious adverse reactions, if any of these syndromes are recognized, the drug should be discontinued immediately:
Hypersensitivity syndrome consisting of cutaneous reaction (such as rash or exfoliative dermatitis), eosinophilia, and one or more of the following: hepatitis, pneumonitis, nephritis, myocarditis, and pericarditis. Fever and lymphadenopathy may be present.
Lupus-like syndrome consisting of positive antinuclear antibody; arthralgia, arthritis, joint stiffness, or joint swelling; and one or more of the following: fever, myalgia, hepatitis, rash, and vasculitis.
Serum sickness-like syndrome consisting of fever; urticaria or rash; and arthralgia, arthritis, joint stiffness, or joint swelling. Eosinophilia may be present.
DRUG INTERACTIONS
Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage.
Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin.
Absorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, and iron-containing preparations.
The concurrent use of tetracycline and methoxyflurane has been reported to result in fatal renal toxicity.
Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective.
Administration of isotretinoin should be avoided shortly before, during, and shortly after minocycline therapy. Each drug alone has been associated with pseudotumor cerebri (see PRECAUTIONS).
Increased risk of ergotism when ergot alkaloids or their derivatives are given with tetracyclines.
Drug And/Or Laboratory Test Interactions
False elevations of urinary catecholamine levels may occur due to interference with the fluorescence test.
Read the entire FDA prescribing information for Dynacin (Minocycline Hydrochloride Tablets)
© Dynacin Patient Information is supplied by Cerner Multum, Inc. and Dynacin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.