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Trulicity vs. Lantus

Are Trulicity and Lantus the Same Thing?

Trulicity (dulaglutide) and Lantus (insulin glargine [rdna origin]) Injection are used to improve glycemic control in adults with type 2 diabetes mellitus.

Lantus is also used to treat type 1 (insulin-dependent) diabetes.

Trulicity and Lantus are different types of diabetes medications. Trulicity is a human GLP-1 receptor agonist and Lantus is a man-made form of a hormone that is produced in the body.

Side effects of Trulicity and Lantus that are similar include weakness/lack of energy and low blood sugar (hypoglycemia).

Side effects of Trulicity that are different from Lantus include nausea, vomiting, abdominal pain or discomfort, decreased appetite, indigestion, diarrhea, frequent bowel movements, fatigue, constipation, gas, bloating, gastroesophageal reflux disease (GERD), feeling unwell (malaise), and belching.

Side effects of Lantus that are different from Trulicity include headache, hunger, sweating, tremors, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, or seizures (severe hypoglycemia can be fatal).

Trulicity may interact with other oral medications taken at the same time.

Lantus may interact with albuterol, clonidine, reserpine, or beta-blockers.

What Are Possible Side Effects of Trulicity?

Common side effects of Trulicity include:

  • nausea,
  • diarrhea,
  • frequent bowel movements,
  • vomiting,
  • abdominal pain or discomfort,
  • decreased appetite,
  • indigestion,
  • fatigue,
  • constipation,
  • gas,
  • bloating,
  • gastroesophageal reflux disease (GERD),
  • weakness/lack of energy,
  • feeling unwell (malaise),
  • belching, and
  • low blood sugar (hypoglycemia).

What Are Possible Side Effects of Lantus?

Common side effects of Lantus include:

  • headache,
  • hunger,
  • weakness,
  • sweating,
  • tremors,
  • irritability,
  • trouble concentrating,
  • rapid breathing,
  • fast heartbeat,
  • fainting, or
  • seizure (severe hypoglycemia can be fatal).

Other common side effects of Lantus include pain, redness, swelling, itching, or thickening of the skin at the injection site. These side effects usually go away after a few days or weeks.

What Is Trulicity?

Trulicity (dulaglutide) is a human GLP-1 receptor agonist used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

What Is Lantus?

Lantus (insulin glargine [rdna origin]) Injection is a man-made form of a hormone that is produced in the body used to treat type 1 (insulin-dependent) or type 2 (non insulin-dependent) diabetes.

What Drugs Interact With Trulicity?

Trulicity may interact with other oral medications. Tell your doctor all medications and supplements you use. During pregnancy, Trulicity should be taken only if prescribed; it is unknown if it would affect a fetus. It is unknown if Trulicity passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Lantus?

Lantus may interact with albuterol, clonidine, reserpine, or beta-blockers. Many other medicines can increase or decrease the effects of insulin glargine on lowering your blood sugar. Tell your doctor all prescription and over-the-counter medications and supplements you use. Tell your doctor if you are pregnant before using Lantus. Discuss a plan to manage blood sugar with your doctor before becoming pregnant. Your doctor may switch the type of insulin you use during pregnancy. It is unknown if this drug passes into breast milk. Insulin needs may change while breastfeeding. Consult your doctor before breast-feeding.

How Should Trulicity Be Taken?

The recommended initiating dose of Trulicity is 0.75 mg once weekly. The maximum recommended dose is 1.5 mg once weekly.

How Should Lantus Be Taken?

Lantus should be administered subcutaneously (under the skin) once a day at the same time every day. Dose is determined by the individual and the desired blood glucose levels.

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