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Ozempic vs. Trulicity

Are Ozempic and Trulicity the Same Thing?

Ozempic (semaglutide) Injection and Trulicity (dulaglutide) are glucagon-like peptide 1 (GLP-1) receptor agonists indicated as adjuncts to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Side effects of Ozempic and Trulicity that are similar include nausea, vomiting, diarrhea, abdominal pain or discomfort, and constipation.

Side effects of Trulicity that are different from Ozempic include frequent bowel movements, decreased appetite, indigestion, fatigue, gas, bloating, gastroesophageal reflux disease (GERD), weakness/lack of energy, feeling unwell (malaise), belching, and low blood sugar (hypoglycemia).

Both Ozempic and Trulicity may interact with other oral medications taken at the same time.

Ozempic may also interact with insulin secretagogues or insulin.

What Are Possible Side Effects of Ozempic?

Common side effects of Ozempic include:

What Are Possible Side Effects of Trulicity?

Common side effects of Trulicity include:

  • nausea,
  • diarrhea,
  • frequent bowel movements,
  • vomiting,
  • abdominal pain or discomfort,
  • decreased appetite,
  • indigestion,
  • fatigue,
  • constipation,
  • gas,
  • bloating,
  • gastroesophageal reflux disease (GERD),
  • weakness/lack of energy,
  • feeling unwell (malaise),
  • belching, and
  • low blood sugar (hypoglycemia).

What Is Ozempic?

Ozempic (semaglutide) Injection is a glucagon-like peptide 1 (GLP-1) receptor agonist indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

What Is Trulicity?

Trulicity (dulaglutide) is a human GLP-1 receptor agonist used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

 

What Drugs Interact With Ozempic?

Ozempic may interact with an insulin secretagogue or insulin, and other oral medications taken at the same time. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Ozempic; it is unknown how it would affect a fetus. It is unknown if Ozempic passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Trulicity?

Trulicity may interact with other oral medications. Tell your doctor all medications and supplements you use. During pregnancy, Trulicity should be taken only if prescribed; it is unknown if it would affect a fetus. It is unknown if Trulicity passes into breast milk. Consult your doctor before breastfeeding.

 

How Should Ozempic Be Taken?

The initial dose of Ozempic is 0.25mg once weekly. After 4 weeks, increase the dose to 0.5 mg once weekly. If after at least 4 weeks additional glycemic control is needed, increase to 1mg once weekly.

How Should Trulicity Be Taken?

The recommended initiating dose of Trulicity is 0.75 mg once weekly. The maximum recommended dose is 1.5 mg once weekly.