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Vistaril vs. Benadryl

Are Vistaril and Benadryl the Same Thing?

Vistaril (hydroxyzine pamoate) and Benadryl (diphenhydramine) are antihistamines with anticholinergic (drying) and sedative properties used to control nausea and vomiting, or to treat allergic skin reactions such as hives or contact dermatitis.

Vistaril is also used as a sedative to treat anxiety and tension, and it is also used together with other medications given for anesthesia.

Benadryl is also used to treat insomnia and mild cases of Parkinsonism.

What Are Possible Side Effects of Vistaril?

Vistaril may cause serious side effects, including:

Tell your doctor if you experience serious side effects of Vistaril including:
  • restless muscle movements in your eyes, tongue, jaw, or neck,
  • tremors (uncontrolled shaking),
  • confusion,
  • or seizures (convulsions).

What Are Possible Side Effects of Benadryl?

Common side effects of Benadryl include:

What is Vistaril?

Vistaril (hydroxyzine pamoate) is an antihistamine with anticholinergic (drying) and sedative properties used as a sedative to treat anxiety and tension. Vistaril is also used together with other medications given for anesthesia. Vistaril may also be used to control nausea and vomiting, or to treat allergic skin reactions such as hives or contact dermatitis. Vistaril is available in generic form.

What is Benadryl?

Benadryl (diphenhydramine) is an antihistamine used to treat allergies, hives, insomnia, motion sickness, and mild cases of Parkinsonism.

 

What Drugs Interact With Vistaril?

Vistaril may interact with probenecid.

Vistaril may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety).

What Drugs Interact With Benadryl?

Benadryl may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety).

Benadryl may also interact with monoamine oxidase inhibitors (MAOIs).

 

How Should Vistaril Be Taken?

The recommended dose of Vistaril for treating itch (pruritus) is 25 mg, 3 or 4 times daily. For sedation, the recommended dose is 50 to 100 mg. The dose to treat anxiety and tension is 50 to 100 mg 4 times daily. Vistaril may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). Tell your doctor all prescription and over-the-counter medications and supplements you use. Vistaril is not recommended for use during pregnancy. It could harm the fetus. Discuss birth control with your doctor. It is unknown if this medication passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

How Should Benadryl Be Taken?

A typical dose of Benadryl is 25-50 mg every 4-6 hours. Benadryl may interact with monoamine oxidase inhibitors (MAOIs), other over-the-counter cough, cold, allergy, or insomnia medications, anxiety or sleep medicines, antidepressants, or any other medications that make you feel drowsy, sleepy, or relaxed. Tell your doctor all medications and supplements you use. Benadryl has not been adequately evaluated in pregnant women. Benadryl is secreted in breast milk. Because of the risk of stimulation and seizures in infants, especially newborns and premature infants, antihistamines should not be used by nursing mothers.