Jatenzo vs. AndroGel

Jatenzo (testosterone undecanoate) and AndroGel (testosterone gel) are androgens indicated for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone.

Side effects of Jatenzo and AndroGel that are similar include nausea and headache.

Side effects of Jatenzo that are different from AndroGel include high red blood cell count (polycythemia), diarrhea, indigestion/heartburn, belching, swelling of extremities, increased hematocrit, enlarged prostate, and high blood pressure (hypertension).

Side effects of AndroGel that are different from Jatenzo include vomiting, dizziness, hair loss, increased hair growth, trouble sleeping, changes in sexual desire, redness/swelling/itching/burning/hardening of the skin where the patch is worn, change in skin color, breast swelling or tenderness, depression, and acne.

Both Jatenzo and AndroGel may interact with insulin, blood thinners, and corticosteroids.

Jatenzo may also interact with medications that increase blood pressure.

Common side effects of Jatenzo include:

• high red blood cell count (polycythemia),
• diarrhea,
• indigestion/heartburn,
• belching,
• swelling of extremities,
• nausea,
• increased hematocrit,
• headache,
• enlarged prostate, and
• high blood pressure (hypertension)

Common side effects of AndroGel include:

• nausea,
• vomiting,
• headache,
• dizziness,
• hair loss,
• increased hair growth,
• trouble sleeping,
• changes in sexual desire,
• redness/swelling/itching/burning/hardening of the skin where the patch is worn,
• change in skin color,
• breast swelling or tenderness,
• depression, or acne

Jatenzo (testosterone undecanoate) is an androgen indicated for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone.

AndroGel (testosterone gel) is a form of the male hormone testosterone used to treat conditions in men that result from a lack of natural testosterone, a naturally occurring male hormone.

Jatenzo may interact with insulin, anticoagulants, corticosteroids, or medications that increase blood pressure. Tell your doctor all medications and supplements you use.

AndroGel may interact with insulin, blood thinners, oxyphenbutazone, or corticosteroids. Tell your doctor all medications you use.

The starting dose of Jatenzo is 237 mg orally once in the morning and once in the evening. The dose of Jatenzo is adjusted to a minimum of 158 mg twice daily and a maximum of 396 mg twice daily.

The recommended starting dose of AndroGel is 5 g once daily to clean, dry, intact skin of the shoulders and upper arms and/or abdomen.