Beovu vs. Avastin

Beovu (brolucizumab-dbll) Injection and Avastin (bevacizumab) are used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD).

Avastin is mainly used to treat a certain type of brain tumor as well as cancers of the kidney, colon, rectum, lung, or breast. Avastin is usually given as part of a combination of cancer medicines.

Beovu and Avastin belong to different drug classes. Beovu is a human vascular endothelial growth factor (VEGF) inhibitor and Avastin is an antiangiogenic drug.

Side effects of Beovu that are different from Avastin include blurred vision, cataracts, bleeding in the eye, eye pain, and eye "floaters."

Side effects of Avastin that are different from Beovu include dry mouth, cough, voice changes, loss of appetite, diarrhea, nausea, vomiting, constipation, mouth sores, headache, back pain, cold symptoms (stuffy nose, sneezing, sore throat), dry or watery eyes, dry or flaky skin, hair loss, changes in your sense of taste, jaw pain/swelling/numbness, loose teeth, and gum infection.

Both Beovu and Avastin may interact with other drugs.

Common side effects of Beovu include:

• blurred vision,
• cataracts,
• bleeding in the eye,
• eye pain, and
• eye "floaters"

Common side effects of Avastin include:

• dry mouth,
• cough,
• voice changes,
• loss of appetite,
• diarrhea,
• nausea,
• vomiting,
• constipation,
• mouth sores,
• headache,
• back pain,
• cold symptoms (stuffy nose, sneezing, sore throat),
• dry or watery eyes,
• dry or flaky skin,
• hair loss,
• changes in your sense of taste,
• jaw pain/swelling/numbness,
• loose teeth, or
• gum infection.

Tell your doctor if you have serious side effects of Avastin including:

• trouble breathing,
• swelling of ankles or feet,
• sudden weight gain,
• fast heartbeat,
• signs of infection (e.g., fever, persistent sore throat),
• muscle cramps,
• muscle loss,
• yellowing eyes or skin,
• frothy or dark urine,
• difficulty urinating, or
• decreased amount of urine.

Beovu (brolucizumab-dbll) Injection is a human vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of Neovascular (Wet) Age-Related Macular Degeneration (AMD).

Avastin (bevacizumab) is an antiangiogenic drug used to treat a certain type of brain tumor as well as cancers of the kidney, colon, rectum, lung, or breast. Avastin is usually given as part of a combination of cancer medicines.

Beovu may interact with other drugs. Tell your doctor all medications and supplements you use.

There may be other drugs that can interact with Avastin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Beovu is administered by intravitreal injection. The recommended dose for Beovu is 6 mg (0.05 mL of 120 mg/mL solution) monthly (approximately every 25-31 days) for the first three doses, followed by one dose of 6 mg (0.05 mL) every 8-12 weeks.

Dose of Avastin varies depending on the type of cancer being treated, and the patient's weight.