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Definition of VEGF
Medically reviewed by Min Clinic Staff | Updated: January 2026
VEGF: Vascular endothelial growth factor, a substance made by cells that stimulates the formation of new blood vessels, a process called angiogenesis. VEGF also acts as a mitogen for vascular endothelial (vessel lining) cells, stimulating these cells to divide and multiply.
VEGF is a polypeptide. It is structurally related to platelet-derived growth factor (PDGF). The gene for VEGF is on chromosome 6p12.