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Lialda vs. Apriso

Are Apriso and Lialda the Same Thing?

Lialda (mesalamine) and Apriso (mesalamine extended-release capsules) are aminosalicylate anti-inflammatory agents used to treat ulcerative colitis, proctitis, and proctosigmoiditis, and also to prevent the symptoms of ulcerative colitis from recurring.

Side effects of Lialda and Apriso are similar and include nausea, vomiting, stomach cramps, diarrhea, gas, fever, sore throat, flu-like symptoms, constipation, headache, dizziness, tired feeling, or skin rash.

Both Lialda and Apriso may interact with azathioprine, mercaptopurine, pentamidine, tacrolimus, amphotericin B, antiviral medicines, cancer medicines, or aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs).

Lialda may also interact with antibiotics.

What Are Possible Side Effects of Lialda?

Common side effects of Lialda include:

  • nausea,
  • vomiting,
  • stomach cramps,
  • diarrhea,
  • gas,
  • fever,
  • sore throat,
  • flu-like symptoms,
  • constipation,
  • headache,
  • dizziness,
  • tired feeling, or
  • skin rash.

Contact your doctor if you experience serious side effects of Lialda including:

  • severe stomach pain,
  • fever,
  • headache, and
  • bloody diarrhea.

What Are Possible Side Effects of Apriso?

Common side effects of Apriso include:

  • diarrhea,
  • headache,
  • nausea,
  • vomiting,
  • gas,
  • fever,
  • sore throat,
  • flu symptoms,
  • runny/stuffy nose,
  • stomach cramps or upset,
  • constipation,
  • dizziness,
  • tired feeling, or
  • skin rash.

Tell your doctor if you have serious side effects of Apriso including:

What Is Lialda?

Lialda (mesalamine) is an anti-inflammatory agent used to treat ulcerative colitis, proctitis, and proctosigmoiditis, and also to prevent the symptoms of ulcerative colitis from recurring.

What Is Apriso?

Apriso (mesalamine extended-release capsules) is an aminosalicylate anti-inflammatory drug used to treat ulcerative colitis, proctitis, and proctosigmoiditis. Apriso is also used to prevent the symptoms of ulcerative colitis from recurring.

What Drugs Interact With Lialda?

Lialda may interact with azathioprine or mercaptopurine, pentamidine, tacrolimus, amphotericin B, antibiotics, antiviral medicines, cancer medicine, aspirin or other NSAIDs. Tell your doctor all medications you are taking. Lialda is not expected to be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication can pass into breast milk and may harm a nursing baby. Do not use this medication if you are breastfeeding.

What Drugs Interact With Apriso?

Apriso may interact with azathioprine, mercaptopurine, pentamidine, tacrolimus, amphotericin B, antibiotics, antiviral medicines, cancer medicines, aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs). Tell your doctor all medications and supplements you use. During pregnancy, Apriso should be used only when prescribed. This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

How Should Lialda Be Taken?

The recommended dosage of Lialda for the induction of remission in adult patients with active, mild to moderate ulcerative colitis is two to four 1.2 g tablets taken once daily with a meal for a total daily dose of 2.4 g or 4.8 g. The recommended dosage for the maintenance of remission is two 1.2 g tablets taken once daily with a meal for a total daily dose of 2.4 g.

How Should Apriso Be Taken?

The recommended dose for maintenance of remission of ulcerative colitis in adult patients is 1.5 g (four Apriso capsules) orally once daily in the morning.

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