Ascor

What Is Ascor?

Ascor (ascorbic acid injection) is vitamin C indicated for the short term (up to 1 week) treatment of scurvy in adult and pediatric patients age 5 months and older for whom oral administration is not possible, insufficient or contraindicated.

What Are Side Effects of Ascor?

Common side effects of Ascor include pain and swelling at the site of infusion. Rapid intravenous administration of Ascor may cause temporary faintness, nausea, lethargy, flushing, dizziness, and headache

Dosage for Ascor

The dose of Ascor for pediatric patients age 5 months to less than 12 months is 50 mg once daily. The dose of Ascor for pediatric patients age 1 year to less than 11 years is 100 mg once daily. The dose of Ascor for adults and pediatric patients age 11 years and older is 200 mg once daily.

What Drugs, Substances, or Supplements Interact with Ascor?

Ascor may interact with antibiotics, amphetamines, certain drugs affected by the pH of the urine (e.g. fluphenazine), and warfarin. Tell your doctor all medications and supplements you use.

Ascor During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Ascor; there are dose adjustments for ascorbic acid (vitamin C) use during pregnancy. It is unknown if Ascor passes into breast milk following intravenous infusion. Consult your doctor before breastfeeding.

Additional Information

Our Ascor (ascorbic acid injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using ascorbic acid and call your doctor at once if you have:

• joint pain, weakness or tired feeling, weight loss, stomach pain;
• chills, fever, increased urge to urinate, painful or difficult urination; or
• severe pain in your side or lower back, blood in your urine.

Common side effects may include:

• heartburn, upset stomach; or
• nausea, diarrhea, stomach cramps.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Ascor (Ascorbic Acid Injection for Intravenous Use)

 

Ascor Professional Information

SIDE EFFECTS

The following adverse reactions are discussed in greater detail in other sections of the labeling:

• Oxalate nephropathy and Nephrolithiasis [see WARNINGS AND PRECAUTIONS]
• Hemolysis in patients with glucose-6-phosphate dehydrogenase deficiency [see WARNINGS AND PRECAUTIONS]

The following adverse reactions associated with the use of ascorbic acid were identified in the literature. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency reliably or to establish a causal relationship to drug exposure:

Administration site reactions: pain and swelling.

ASCOR should not be rapidly administered. Rapid intravenous administration (>250 mg/minute) of ASCOR may cause temporary faintness or nausea, lethargy, flushing, dizziness, and headache (the recommended infusion rates of diluted ASCOR solution are 1.3 mg/minute (Pediatric Patients age 5 months to less than 12 months), 3.3 mg/minute (Pediatric Patients age 1 year to less than 11 years) and 33 mg/minute (Adults and Pediatric Patients 11 years and older) [see DOSAGE AND ADMINISTRATION] ) .

Acute and chronic oxalate nephropathy have occurred with prolonged administration of high doses of ascorbic acid [see WARNINGS AND PRECAUTIONS]. In patients with glucose-6-phosphate dehydrogenase deficiency severe hemolysis has occurred [see WARNINGS AND PRECAUTIONS].

Read the entire FDA prescribing information for Ascor (Ascorbic Acid Injection for Intravenous Use)