Apresazide
- Generic Name: hydralazine and hydrochlorothiazide
- Brand Name: Apresazide
Apresazide (Hydralazine and Hydrochlorothiazide) side effects drug center
Apresazide Side Effects Center
What Is Aprezaside?
Apresazide (hydralazine HCI and hydrochlorothiazide) is an antihypertensive-diuretic combination used to treat hypertension (high blood pressure). The brand name Apresazide is discontinued, but generic versions may be available.
What Are Side Effects of Aprezaside?
Common side effects of Apresazide (hydralazine HCI and hydrochlorothiazide) include
- headache
- pounding/fast heartbeat
- dizziness
- loss of appetite
- nausea
- vomiting
- diarrhea
- heart palpitations
- chest pain
- or abdominal pain as your body adjusts to the medication.
Other side effects of Apresazide (hydralazine HCI and hydrochlorothiazide) include decreased sexual ability or increased sensitivity to the sun.
Dosage for Aprezaside
The usual dosage is one hydralazine HCl and hydrochlorothiazide capsule twice daily, the strength depending upon individual requirements.
What Drugs, Substances, or Supplements Interact with Aprezaside?
Apresazide may interact with MAO inhibitors, other antihypertensives, digitalis, steroids or ACTH, insulin, norepinephrine, tubocurarine, lithium, methyldopa, or nonsteroidal anti-inflammatory drugs (NSAIDs). Tell your doctor all medications and supplements you use.
Aprezaside During Pregnancy or Breastfeeding
During pregnancy, Apresazide should be used only if prescribed. Tell your doctor if you are pregnant or plan to become pregnant before using this drug. Consult your doctor before breastfeeding.
Additional Information
Our Apresazide (hydralazine HCI and hydrochlorothiazide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
Apresazide Consumer Information
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- chest pain or pressure, pain spreading to your jaw or shoulder;
- fast or pounding heartbeats;
- a light-headed feeling, like you might pass out;
- numbness, tingling, or burning pain in your hands or feet;
- painful or difficult urination;
- little or no urination; or
- lupus-like syndrome--joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color.
Common side effects may include:
- chest pain, fast heart rate;
- headache; or
- nausea, vomiting, diarrhea, loss of appetite.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Apresazide (Hydralazine and Hydrochlorothiazide)
Apresazide Professional Information
SIDE EFFECTS
Adverse reactions are usually reversible upon reduction of dosage or discontinuation of hydralazine HCI and hydrochlorothiazide. Whenever adverse reactions are moderate or severe, it may be necessary to discontinue the drug.
Hydralazine
The following adverse reactions have been observed, but there has not been enough systematic collection of data to support an estimate of their frequency.
Common
Headache, anorexia, nausea, vomiting, diarrhea, palpitations, tachycardia, angina pectoris.
Less Frequent
Digestive: Constipation, paralytic ileus. Cardiovascular: Hypotension, paradoxical pressor response, and edema. Respiratory: Dyspnea. Neurologic: Peripheral neuritis, evidenced by paresthesia, numbness, and tingling; dizziness; tremors; muscle cramps; psychotic reactions characterized by depression, disorientation, or anxiety. Genitourinary: Difficulty in urination. Hematologic: Blood dyscrasias, consisting of reduction in hemoglobin and red cell count, leukopenia, agranulocytosis, purpura, lymphadenopathy, splenomegaly. Hypersensitive Reactions: Rash, urticaria, pruritus, fever, chills, arthralgia, eosinophilia, and rarely, hepatitis. Other: Nasal congestion, flushing, lacrimation, and conjunctivitis.Hydrochlorothiazide
The following adverse reactions have been observed but there has not been enough systematic collection of data to support an estimate of their frequency. Consequently the reactions are categorized by organ systems and are listed in decreasing order of severity and not frequency.
Digestive: Pancreatitis, jaundice (intrahepatic cholestatic), sialadenitis, vomiting, diarrhea, cramping, nausea, gastric irritation, constipation, anorexia. Cardiovascular: Orthostatic hypotension (may be potentiated by alcohol, barbiturates, or narcotics). Neurologic: Vertigo, dizziness, transient blurred vision, headache, paresthesia, xanthopsia, weakness, and restlessness. Musculoskeletal: Muscle spasm. Hematologic: Aplastic anemia, agranulocytosis, leukopenia, and thrombocytopenia. Metabolic: Hyperglycemia, glycosuria, and hyperuricemia. Hypersensitive Reactions: Necrotizing angitis, Stevens-Johnson syndrome, respiratory distress including pneumonitis and pulmonary edema, purpura, urticaria, rash, photosensitivity.Read the entire FDA prescribing information for Apresazide (Hydralazine and Hydrochlorothiazide)
© Apresazide Patient Information is supplied by Cerner Multum, Inc. and Apresazide Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.