Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Splenomegaly
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Splenomegaly: Abnormal enlargement of the spleen. Splenomegaly is a sign of an underlying condition, such as severe liver disease, leukemia, or mononucleosis. Patients with splenomegaly should avoid activities that risk trauma to the abdomen, including contact sports, because of risk of bleeding from the injured spleen.
Need Expert Advice on Your Condition?
Get a personalized video breakdown and treatment plan from our senior neurosurgeons using your MRI/CT scans.
👉 Request MRI Review