Pyriton
Pyriton - General Information
One of the histamine H1 antagonists with little sedative action. It is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus. [PubChem]
Pharmacology of Pyriton
Pyriton is an antihistamine used to treat allergic conditions such as hay fever or urticaria. It is generally sold in combination with other medications, rather than as a stand-alone drug.
Pyriton for patients
- Products containing antihistamines may cause drowsiness.
- Patients should not engage in activities requiring mental alertness, such as driving or operating machinery or appliances.
- Alcohol or other sedative drugs may enhance the drowsiness caused by antihistamines.
- Patients should not take Pheniramine Tablets if they are receiving a monoamine oxidase inhibitor or within 2 weeks of stopping such treatment.
- This medication should not be given to children less than 12 years of age.
Pyriton Interactions
Pyriton Contraindications
Antihistamines should not be used to treat lower respiratory tract symptoms, including asthma. This product is contraindicated in patients with narrow-angle glaucoma or urinary retention, and in patients receiving monoamine oxidase (MAO) inhibitor therapy or within 2 weeks of stopping such treatment. It is also contraindicated in patients with severe hypertension, severe coronary artery disease, hyperthyroidism, and in those who have shown hypersensitivity or idiosyncrasy to its components, to adrenergic agents, or to other drugs of similar chemical structures. Manifestations of patient idiosyncrasy to adrenergic agents include: insomnia, dizziness, weakness, tremor, or arrhythmias.
Additional information about Pyriton
Pyriton Indication: Used to treat allergic conditions such as hay fever or urticaria.
Mechanism Of Action: Antihistamines such as pheniramine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Pheniramine
Synonyms: 2-(alpha-(2-Dimethylaminoethyl)benzyl)pyridine; 2-(3-Dimethylamino-1-phenylpropyl)pyridine; 1-Phenyl-1-(2-pyridyl)-3-dimethylaminopropane; 2-[.alpha.-(2-Dimethylaminoethyl)benzyl]pyridine; 2-[.alpha.-[2-(Dimethylamino)ethyl]benzyl]pyridine; Dimethyl(3-phenyl-3-(2-pyridyl)propyl)amine; Feniramina [inn-spanish]; Feniramine; Pheniraminum [inn-latin]; Propheniramine; Prophenpyridamine
Drug Category: Anti-Allergic Agents; Antipruritic Agents; Histamine H1 Antagonists
Drug Type: Small Molecule; Approved
Other Brand Names containing Pheniramine: AVIL; Inhiston; Metron; Pyriton; Trimeton; Tripoton;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatic hydroxylation, demethylation and glucuronidation.
Half Life: Not Available
Dosage Forms of Pyriton: Powder Oral
Tablet Oral
Solution Oral
Solution / drops Oral
Chemical IUPAC Name: N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine
Chemical Formula: C16H20N2
Pheniramine on Wikipedia: https://en.wikipedia.org/wiki/Pheniramine
Organisms Affected: Humans and other mammals
