Nolahist
Nolahist - General Information
Nolahist is an antihistamine. Nolahist blocks the effects of the naturally occurring chemical histamine in your body. Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold.
Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.
Pharmacology of Nolahist
Nolahist is an antihistamine. Nolahist blocks the effects of the naturally occurring chemical histamine in your body.
Nolahist for patients
- Products containing antihistamines may cause drowsiness.
- Patients should not engage in activities requiring mental alertness, such as driving or operating machinery or appliances.
- Alcohol or other sedative drugs may enhance the drowsiness caused by antihistamines.
- Patients should not take Phenindamine Tablets if they are receiving a monoamine oxidase inhibitor or within 2 weeks of stopping such treatment.
- This medication should not be given to children less than 12 years of age.
Nolahist Interactions
Nolahist Contraindications
Antihistamines should not be used to treat lower respiratory tract symptoms, including asthma. This product is contraindicated in patients with narrow-angle glaucoma or urinary retention, and in patients receiving monoamine oxidase (MAO) inhibitor therapy or within 2 weeks of stopping such treatment. It is also contraindicated in patients with severe hypertension, severe coronary artery disease, hyperthyroidism, and in those who have shown hypersensitivity or idiosyncrasy to its components, to adrenergic agents, or to other drugs of similar chemical structures. Manifestations of patient idiosyncrasy to adrenergic agents include: insomnia, dizziness, weakness, tremor, or arrhythmias.
Additional information about Nolahist
Nolahist Indication: Used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold.
Mechanism Of Action: Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Drug Interactions: Not Available
Food Interactions: Take with food to reduce irritation.
Avoid alcohol.
Generic Name: Phenindamine
Synonyms: Fenindamina [inn-spanish]; Phenindaminum [inn-latin]; Phenindiamine
Drug Category: Antihistamines; Histamine H1 Antagonists
Drug Type: Small Molecule; Approved
Other Brand Names containing Phenindamine: Nolahist; Thephorin;
Absorption: Not Available
Toxicity (Overdose): Symptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Nolahist: Not Available
Chemical IUPAC Name: 2-methyl-9-phenyl-1,3,4,9-tetrahydroindeno[2,3-c]pyridine
Chemical Formula: C19H19N
Phenindamine on Wikipedia: Not Available
Organisms Affected: Humans and other mammals
