Brintellix (Trintellix) vs. Wellbutrin

• Are Brintellix (Trintellix) and Wellbutrin the Same Thing?
• What Are Possible Side Effects of Brintellix (Trintellix)?
• What Are Possible Side Effects of Wellbutrin?
• What Is Brintellix (Trintellix)?
• What Is Wellbutrin?
• What Drugs Interact with Brintellix (Trintellix)?
• What Drugs Interact with Wellbutrin?
• How Should Brintellix (Trintellix) Be Taken?
• How Should Wellbutrin Be Taken?

Brintellix (vortioxetine) and Wellbutrin (bupropion) are antidepressants used to treat major depressive disorder (MDD).

Wellbutrin is also used to treat seasonal affective disorder.

The brand name Brintellix was changed to Trintellix in June 2016 because of confusion with the name of an antiplatelet drug called Brilinta (ticagrelor).

Common side effects of Brintellix (Trintellix) include:

• nausea,
• diarrhea,
• constipation,
• vomiting,
• sexual dysfunction,
• dry mouth,
• gas,
• dizziness,
• abnormal dreams, and
• itching.

Common side effects of Wellbutrin include:

• agitation,
• dry mouth,
• insomnia,
• headache,
• nausea,
• vomiting,
• constipation,
• stomach pain,
• dizziness,
• ringing in the ears,
• vision problems or blurred vision,
• loss of interest in sex,
• sore throat,
• muscle pain,
• itching or skin rash,
• increased sweating,
• increased urination,
• tremor,
• changes in appetite,
• weight loss or gain,
• joint aches,
• strange taste in the mouth,
• diarrhea, and
• seizures (especially at higher doses).

Brintellix (vortioxetine) is an antidepressant used to treat major depressive disorder (MDD).

Wellbutrin is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder.

Brintellix may interact with monoamine oxidase inhibitors (MAOIs), SSRIs, SNRIs, triptans, buspirone, tramadol, tryptophan, bupropion, fluoxetine, paroxetine, quinidine, rifampicin, carbamazepine, or phenytoin. Tell your doctor all medications and supplements you use. Tell your doctor if you become pregnant or intend to become pregnant during therapy with Brintellix.

Wellbutrin may interact with insulin, blood thinners, and asthma medications. Wellbutrin may also interact with many medications including heart or blood pressure medications, HIV or AIDS medications, seizure medications, other antidepressants, medicines to treat a psychiatric disorder, antibiotics, antihistamines that make you sleepy, bronchodilators, birth control pills or hormone replacement estrogens, bladder or urinary medications, diet pills, stimulants, ADHD medications, oral diabetes medication, medicines for nausea/vomiting/motion sickness, medications to treat or prevent malaria, medicines to treat Parkinson's disease, medication for restless leg syndrome, medication for pituitary gland tumor, medicines used to prevent organ transplant rejection, narcotics, numbing medicines, steroids, theophylline, or ulcer or irritable bowel medications.

The recommended starting dose of Brintellix is 10 mg taken orally once daily.

• Take Wellbutrin exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Wellbutrin without talking with your healthcare provider first.
• Swallow Wellbutrin tablets whole. Do not chew, cut, or crush Wellbutrin tablets.
• Take Wellbutrin at the same time each day.
• Take your doses of Wellbutrin at least 6 hours apart.
• You may take Wellbutrin with or without food.
• If you miss a dose, do not take an extra dose to make up for the dose you missed. Wait and take your next dose at the regular time. This is very important. Too much Wellbutrin can increase your chance of having a seizure.
• If you take too much Wellbutrin, or overdose, call your local emergency room or poison control center right away.
• Do not take any other medicines while taking Wellbutrin unless your healthcare provider has told you it is okay.
• If you are taking Wellbutrin for the treatment of major depressive disorder, it may take several weeks for you to feel that Wellbutrin is working. Once you feel better, it is important to keep taking Wellbutrin exactly as directed by your healthcare provider. Call your healthcare provider if you do not feel Wellbutrin is working for you.