Lidoderm vs. Duragesic

• Are Lidoderm and Duragesic the Same Thing?
• What Are Possible Side Effects of Lidoderm?
• What Are Possible Side Effects of Duragesic?
• What is Lidoderm?
• What is Duragesic?
• What Drugs Interact with Lidoderm?
• What Drugs Interact with Duragesic?
• How Should Lidoderm Be Taken?
• How Should Duragesic Be Taken?

Lidoderm (lidocaine patch 5%) and Duragesic (fentanyl) are medications used to relieve different types of pain.

Lidoderm is a topical medication generally used to relieve nerve pain after shingles (post-herpetic neuralgia).

Duragesic is a transdermal patch for systemic administration of pain medication, indicated for the management of severe pain in patients who require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

Lidoderm and Duragesic belong to different drug classes. Lidoderm is a topical anesthetic and Duragesic is an opioid analgesic.

Common side effects of Lidoderm include:

• irritation,
• redness,
• swelling,
• blisters,
• numbness, or
• changes in skin color at the site of application.

Contact your doctor if you experience serious side effects of Lidoderm including

• irregular heartbeats,
• drowsiness,
• confusion, tremors,
• seizures (convulsions), or
• blurred vision.

Common side effects of Duragesic include:

• nausea
• vomiting
• drowsiness
• dizziness
• vertigo
• insomnia
• constipation
• increased sweating
• fatigue
• feeling cold
• weight loss
• headache
• diarrhea
• palpitations
• ear problems
• abdominal pain
• dry mouth
• feeling unwell (malaise)
• weakness
• swelling of the extremities
• muscle spasms
• depression
• itching, and
• rash

Lidoderm (lidocaine patch 5%) is a local anesthetic used to relieve nerve pain after shingles (infection with the herpes zoster virus). This type of pain is called post-herpetic neuralgia.

Duragesic (fentanyl) Transdermal System for transdermal administration is an opioid analgesic indicated for the management of pain in opioid-tolerant patients, severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Duragesic (fentanyl) Transdermal System is available in generic form.

Lidoderm may interact with anti-arrhythmic drugs or other local anesthetic products.

Duragesic may interact with other CNS depressants (including sedatives, hypnotics, tranquilizers, general anesthetics, phenothiazines, other opioids, and alcohol), CYP3A4 inhibitors or inducers, monoamine oxidase (MAO) inhibitors, pentazocine, nalbuphine, butorphanol, buprenorphine, and anticholinergics.

Apply Lidoderm to intact skin to cover the most painful area. Apply up to three patches, only once for up to 12 hours within a 24-hour period.

Duragesic (fentanyl) Transdermal System is available in doses of 12 mcg/hr, 25 mcg/hr, 50 mcg/hr, 75 mcg/hr, and 100 mcg/hr.