Mannitol vs. Lasix

• Are Lasix and Mannitol the Same Thing?
• What Are Possible Side Effects of Mannitol?
• What Are Possible Side Effects of Lasix?
• What Is Mannitol?
• What Is Lasix?
• What Drugs Interact with Mannitol?
• What Drugs Interact with Lasix?
• How Should Mannitol Be Taken?
• How Should Lasix Be Taken?

Mannitol injection and Lasix (furosemide) are diuretics used to treat renal (kidney) failure and other conditions.

Mannitol is also used to increase urine production, and to treat or prevent medical conditions caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma).

Lasix is also used to treat excessive fluid accumulation (edema) caused by congestive heart failure, liver failure, and nephritic syndrome. Lasix may be used with antihypertensive drugs to control high blood pressure (hypertension).

Side effects of mannitol and Lasix that are similar include diarrhea, thirst, and dizziness.

Side effects of mannitol that are different from Lasix include headache, nausea, vomiting, dry mouth, dehydration, blurred vision, runny nose, arm pain, chills, low blood pressure (hypotension), hives, irregular heart beat, electrolyte imbalance, and injection site reactions (irritation, pain, swelling).

Side effects of Lasix that are different from mannitol include increased urination, muscle cramps, itching or rash, weakness, spinning sensation, stomach pain, and constipation.

Mannitol may interact with other drugs.

Lasix may interact with sucralfate, cisplatin, cyclosporine, ethacrynic acid, lithium, methotrexate, phenytoin, antibiotics, heart or blood pressure medications, laxatives, salicylates such as aspirin, or steroids.

Common side effects of Mannitol include:

• headache,
• nausea,
• diarrhea,
• vomiting,
• dry mouth,
• thirst,
• dehydration,
• blurred vision,
• nausea,
• vomiting,
• runny nose,
• arm pain,
• chills,
• dizziness,
• low blood pressure (hypotension),
• hives,
• irregular heart beat,
• electrolyte imbalance, and
• irritation/pain/swelling at the injection site.

Common side effects of Lasix include:

• increased urination,
• thirst,
• muscle cramps,
• itching or rash,
• weakness,
• dizziness,
• spinning sensation,
• diarrhea,
• stomach pain, and
• constipation.

Serious side effects of Lasix include:

• dehydration,
• dark urine,
• clay-colored stools,
• nausea,
• vomiting,
• fever,
• jaundice (yellowing of skin or eyes),
• electrolyte abnormalities,
• loss of appetite, and
• rapid weight loss.

Mannitol I.V. (mannitol injection) is a diuretic used to increase urine production, and to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure).

Lasix (furosemide) is an anthranilic acid derivative that is used as a strong diuretic in adults and children to treat excessive fluid accumulation (edema) caused by congestive heart failure, liver failure, renal failure, and nephritic syndrome. Lasix may be used with antihypertensive drugs to control high blood pressure (hypertension).

Mannitol may interact with other drugs. Tell your doctor all medications and supplements you use.

Lasix may interact with lithium or steroids.

Lasix may also interact with sucralfate, cisplatin, cyclosporine, ethacrynic acid, methotrexate, phenytoin, antibiotics, heart or blood pressure medications, laxatives, or salicylates such as aspirin.

The usual adult dosage of Mannitol ranges from 50 to 200 g in a 24-hour period, but in most instances an adequate response will be achieved at a dosage of approximately 100 g/24 hours.

Lasix is available in tablet (20 to 80 mg) and IV forms. Dosage is determined by the patient's physician and varies according to how much fluid and how fast the fluid should be removed. Patients with poor renal function usually require higher doses; doses in children are weight-based. Lasix may interact with sucralfate, cisplatin, cyclosporine, ethacrynic acid, lithium, methotrexate, phenytoin, antibiotics, heart or blood pressure medications, laxatives, salicylates such as aspirin, or steroids. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant while using Lasix; it is unknown if it will harm a fetus. Lasix passes into breast milk and may harm a nursing baby. Lasix may also slow breast milk production. Consult your doctor before breastfeeding.