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Toradol vs. Dilaudid

Are Toradol and Dilaudid the Same Thing?

Toradol (ketorolac tromethamine) and Dilaudid (hydromorphone hydrochloride) and Dilaudid Injection (also termed Dilaudid HP) are pain relievers used to treat moderate to severe pain.

Toradol is also used to treat inflammation.

Toradol and Dilaudid are different types of pain relievers. Toradol is a nonsteroidal anti-inflammatory drug (NSAID) and Dilaudid is an opioid analgesic (opiate).

The brand name Toradol is no longer available in the U.S. Generic versions may be available.

What Are Possible Side Effects of Toradol?

Common side effects of Toradol include:

What Are Possible Side Effects of Dilaudid?

Common side effects of Dilaudid include:

Serious side effects of Dilaudid include

  • shallow, weak, or very slow breathing,
  • trouble breathing,
  • slow heart rate,
  • confusion,
  • lightheadedness or fainting,
  • seizures (convulsions),
  • cold clammy skin,
  • pounding heartbeats or fluttering in your chest,
  • wheezing,
  • confusion,
  • severe weakness or drowsiness,
  • mental/mood changes (such as agitations, confusion, hallucinations),
  • severe stomach or abdominal pain,
  • difficulty urinating, or
  • death.

After a few weeks of use, patients may develop both tolerance and physical dependence on Dilaudid and may need to be slowly weaned off the drug to avoid withdrawal symptoms.

What is Toradol?

Toradol (ketorolac tromethamine) is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat moderately severe pain and inflammation, usually after surgery. Toradol works by blocking the production of prostaglandins, compounds that cause pain, fever, and inflammation. The brand name Toradol is no longer available in the U.S. Generic versions may be available.

What is Dilaudid?

Dilaudid (hydromorphone hydrochloride) and Dilaudid Injection (also termed Dilaudid HP) are the tablet, liquid and IV forms of an opioid analgesic used for control of moderate to severe pain.

 

What Drugs Interact With Toradol?

Drug interactions may occur with lithium, ACE inhibitors, warfarin, and medications used to treat high uric acid levels. Warnings may apply to individuals who have ulcers, cardiovascular disease, kidney disease, and bleeding disorders. People who are taking aspirin or NSAIDs should not take Toradol because of the cumulative risk of inducing serious NSAID-related side effects.

What Drugs Interact With Dilaudid?

Opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs.

Dilaudid may also interact with atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, bladder or urinary medicines, bronchodilators, irritable bowel medicines, or ulcer medications.

 

How Should Toradol Be Taken?

Toradol is available as a 10 mg tablet and a solution (30 mg per ml) for intravenous (IV) or intramuscular (IM) administration. Toradol solution is administered as a single 15- to 60-mg dose once every 6 hours not to exceed 60 or 120 mg a day. The recommended oral dose is one to two Toradol tablets initially followed by one tablet every 4-6 hours, not to exceed 40 mg daily. Toradol should not be used for more than 5 days.

How Should Dilaudid Be Taken?

Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals. Initiate the dosing regimen for each patient individually, taking into account the patient's severity of pain, patient response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse. Monitor patients closely for respiratory depression, especially within the first 24-72 hours of initiating therapy and following dosage increases with DILAUDID INJECTION or DILAUDID-HP INJECTION and adjust the dosage accordingly.