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Remeron vs. Cymbalta

Are Remeron and Cymbalta the Same Thing?

Remeron (mirtazapine) and Cymbalta (duloxetine) are antidepressants used to treat depression.

Remeron has also been used to treat nausea, anxiety, post traumatic stress syndrome, and used as an appetite stimulant.

Cymbalta is also used for treating anxiety disorder, and pain associated with diabetic peripheral neuropathy or fibromyalgia.

Remeron and Cymbalta belong to different drug classes. Remeron is a tetracyclic antidepressant and Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SNRI).

What Are Possible Side Effects of Remeron?

Common side effects of Remeron include:

  • drowsiness
  • increased appetite
  • weight gain
  • dizziness, and
  • nausea

Tell your doctor if you experience serious side effects of Remeron including agitation, hallucinations, fever, fast or uneven heart rate, loss of coordination or feeling unsteady, stiff muscles, confusion, tremors, flu symptoms, memory problems, weakness, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, sweating, feeling like you might pass out, chills, body aches, white patches or sores inside your mouth or on your lips, headache, or trouble concentrating.

What Are Possible Side Effects of Cymbalta?

Common side effects of Cymbalta include:

Some patients may experience withdrawal reactions such anxiety, nausea, nervousness, and insomnia.

What is Remeron?

Remeron is a prescription medicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of not treating it. You should discuss all treatment choices with your healthcare provider.

Talk to your healthcare provider if you do not think that your condition is getting better with Remeron treatment.

What is Cymbalta?

Cymbalta (duloxetine) is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for treating depression, anxiety disorder, and pain associated with diabetic peripheral neuropathy or fibromyalgia.

What Drugs Interact With Remeron?

Remeron may interact with other drugs that make you sleepy (cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety), cimetidine, lithium, blood thinners, other antidepressants, or migraine headache medicines.

Remeron may also interact with conivaptan, imatinib, isoniazid, St. John's wort, tramadol, antibiotics, antifungal medications, heart or blood pressure medications, HIV/AIDS medicines, or seizure medications.

What Drugs Interact With Cymbalta?

Cymbalta may also interact with any medicine for pain, arthritis, fever, or swelling (including aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, piroxicam, nabumetone, etodolac, and others), buspirone, diuretics (water pills), tryptophan.

How Should Remeron Be Taken?

  • Take REMERON exactly as prescribed. Your healthcare provider may need to change the dose of REMERON until it is the right dose for you.
  • Take REMERON at the same time each day, preferably in the evening at bedtime.
  • Swallow REMERON as directed.
  • It is common for antidepressant medicines such as REMERON to take up to a few weeks before you start to feel better. Do not stop taking REMERON if you do not feel results right away.
  • Do not stop taking or change the dose of REMERON without first talking to your doctor, even if you feel better.
  • REMERON may be taken with or without food.
  • If you miss a dose of REMERON, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of REMERON at the same time.
  • If you take too much REMERON, call your healthcare provider or poison control center right away, or get emergency treatment. The signs of an overdose of REMERON (without other medicines or alcohol) include:
    • confusion,
    • memory problems
    • drowsiness
    • increased heart rate.

The symptoms of a possible overdose may include changes to your heart rhythm (fast, irregular heartbeat) or fainting, which could be symptoms of a life-threatening condition known as Torsades de Pointes.

How Should Cymbalta Be Taken?

The recommended dose of Cymbalta for treating depression is 20 or 30 mg twice daily or 60 mg once daily.

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