Vimovo vs. Motrin (Ibuprofen)

Vimovo (naproxen and esomeprazole magnesium) and ibuprofen are used to treat signs and symptoms of rheumatoid arthritis and osteoarthritis.

Vimovo is also used to treat signs and symptoms of and ankylosing spondylitis and forms of arthritis when there is a high risk for stomach bleeding/ulcer.

Motrin (Ibuprofen) is also used to treat primary dysmenorrhea.

Vimovo and Ibuprofen both contain a nonsteroidal anti-inflammatory drug (NSAID). Vimovo also contains a proton pump inhibitor (PPI).

Brand names for ibuprofen include Advil and Motrin. Motrin (Ibuprofen) is available over-the-counter (OTC) and as a generic.

Side effects of Vimovo and Ibuprofen that are similar include stomach pain, heartburn, nausea, gas, diarrhea, constipation, and dizziness.

Side effects of Vimovo that are different from ibuprofen include upset stomach ad drowsiness.

Side effects of ibuprofen that are different from Vimovo include bloating, vomiting, headache, nervousness, skin itching or rash, blurred vision, and ringing in the ears.

Both Vimovo and ibuprofen may interact with SSRI/SNRI antidepressants, lithium, blood thinners, and steroids.

Vimovo may also interact with amphetamines, oral bisphosphonates, anti-platelet drugs, clopidogrel, HIV drugs, probenecid, digoxin, azole antifungals, iron supplements, other products containing naproxen, and other proton pump inhibitors.

Motrin (Ibuprofen) may also interact with alcohol, aspirin, cold/allergy or pain medicines that contain aspirin or other NSAIDs, methotrexate, heart or blood pressure medications, and diuretics (water pills).

Side effects of Vimovo include:

• upset stomach,
• stomach pain,
• heartburn,
• nausea,
• gas,
• diarrhea,
• constipation,
• drowsiness, or
• dizziness.

Tell your doctor if you have serious side effects of Vimovo including:

• easy bruising or bleeding,
• lightheadedness,
• fainting,
• signs of a lung infection (such as fever, cough, trouble breathing),
• difficult or painful swallowing,
• swelling of the hands or feet,
• sudden or unexplained weight gain,
• symptoms of a low magnesium blood level (such as unusually fast/slow/irregular heartbeat, or persistent muscle spasms, seizures).

Common side effects of Motrin (Ibuprofen) include:

• stomach pain,
• constipation,
• diarrhea,
• bloating,
• gas,
• heartburn,
• nausea,
• vomiting,
• dizziness,
• headache,
• nervousness,
• skin itching or rash,
• blurred vision, or
• ringing in the ears.

Other side effects of Motrin may occur. Consult your physician if you experience any possible side effects of Motrin.

Vimovo (naproxen and esomeprazole magnesium) is a combination of a nonsteroidal anti-inflammatory drug (NSAID) and a proton pump inhibitor (PPI) used to treat signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis when there is a high risk for stomach bleeding/ulcer.

Motrin (Ibuprofen) is a nonsteroidal anti-inflammatory drug (NSAID) indicated for relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis, for relief of mild to moderate pain, and for treatment of primary dysmenorrhea. A generic formulation is available.

Vimovo may interact with amphetamines, oral bisphosphonates, blood thinners, anti-platelet drugs, SSRI/SNRI antidepressants, clopidogrel, corticosteroids, HIV drugs, lithium, probenecid, digoxin, azole antifungals, iron supplements, other products containing naproxen, other proton pump inhibitors. Check medicine labels as many contain pain relievers/fever reducers similar to Vimovo and may increase the risk of side effects if taken together. Tell your doctor all medications and supplements you are taking.

Motrin (Ibuprofen) may interact with antidepressants, blood thinners, lithium, methotrexate, diuretics (water pills), steroids, aspirin or other NSAIDs, or heart or blood pressure medications. Tell your doctor all medications and supplements you use. Naprosyn may cause premature closing of the ductus arteriosus in the fetus and does enter breast milk; avoidance of the drug in pregnant and breastfeeding women is suggested.

Naproxen may interact with antidepressants, blood thinners, lithium, methotrexate, diuretics (water pills), steroids, aspirin or other NSAIDs, or heart or blood pressure medications. Tell your doctor all medications and supplements you use. Naprosyn may cause premature closing of the ductus arteriosus in the fetus and does enter breast milk; avoidance of the drug in pregnant and breastfeeding women is suggested.

The dosage of Vimovo is one tablet twice daily, 375 mg ibuprofen/20 mg esomeprazole or 500 mg ibuprofen/20 mg esomeprazole.

The recommended dose of Motrin should be adjusted to suit individual patients needs but should not exceed 3200 mg in the total daily dose. Use of alcohol and smoking could increase side effects. Safe use of Motrin for use by children has not been established. It is not known whether ibuprofen is harmful to an unborn baby.