Uloric vs. Gloperba

• Are Uloric and Gloperba the Same Thing?
• What Are Possible Side Effects of Uloric?
• What Are Possible Side Effects of Gloperba?
• What Is Uloric?
• What Is Gloperba?
• What Drugs Interact with Uloric?
• What Drugs Interact with Gloperba?
• How Should Uloric Be Taken?
• How Should Gloperba Be Taken?

Uloric (febuxostat) and Gloperba (colchicine) are used to treat gout.

Uloric and Gloperba belong to different drug classes. Uloric is a xanthine oxidase inhibitor and Gloperba is an anti-gout agent.

Side effects of Uloric and Gloperba that are similar include nausea.

Side effects of Uloric that are different from Gloperba include joint pain/swelling/stiffness, skin rash, and dizziness.

Side effects of Gloperba that are different from Uloric include gastrointestinal symptoms, including diarrhea, vomiting, and abdominal pain.

Uloric may interact with theophylline, azathioprine, or mercaptopurine.

Gloperba may interact with grapefruit juice, erythromycin, verapamil, cyclosporine, clarithromycin, ketoconazole, HMG-CoA reductase inhibitors (statins), and fibrates.

Common side effects of Uloric include:

• joint pain/swelling/stiffness,
• nausea,
• skin rash, and
• dizziness.

Serious side effects of Uloric include:

• cardiovascular events including myocardial infarction,
• liver enzyme abnormalities,
• weakness,
• numbness in extremities, and
• shortness of breath.

Common side effects of Gloperba include:

• gastrointestinal symptoms,
• including diarrhea,
• nausea,
• vomiting, and
• abdominal pain

Uloric (febuxostat) is a xanthine oxidase inhibitor used to treat excess uric acid in the blood (hyperuricemia) in patients with gout.

Gloperba (colchicine) Oral Solution is an anti-gout agent indicated for prevention of gout flares in adults.

Uloric may interact with theophylline, azathioprine, or mercaptopurine. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant while using Uloric; it is unknown if Uloric will harm a fetus. It is unknown if Uloric passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding. Safety and effectiveness in pediatric patients 18 years of age or less have not been done.

Gloperba may interact with grapefruit juice, erythromycin, verapamil, cyclosporine, clarithromycin, ketoconazole, HMG-CoA reductase inhibitors (statins), and fibrates. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Gloperba; it is not expected to harm a fetus at normal doses. Gloperba may very rarely cause infertility in males. Gloperba passes into breast milk. Consult your doctor before breastfeeding.

Uloric (febuxostat) is available in tablets in strengths of 40 or 80 mg. Starting dosage is usually 40mg once daily.

The dose of Gloperba is 0.6 mg (5 mL) once or twice daily.