Trintellix vs. Viibryd

Trintellix (vortioxetine) and Viibryd (vilazodone hydrochloride) are selective serotonin reuptake inhibitor (SSRI) type antidepressants used to treat major depressive disorder (MDD).

Common side effects of Trintellix include:

• nausea
• diarrhea
• dry mouth
• constipation
• vomiting
• gas
• dizziness
• abnormal dreams
• itching, and
• decreased sexual desire

Antidepressants such as Trintellix increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. Tell your doctor if you experience any thoughts of suicide while taking Trintellix.

Common side effects of Viibryd include:

• diarrhea,
• nausea,
• vomiting, and
• sleep problems (insomnia).

Contact your doctor if you have serious side effects of Viibryd including:

• easy bruising,
• unusual bleeding (nose, mouth, vagina, or rectum),
• blood in your urine or stools,
• purple or red pinpoint spots under your skin,
• agitation,
• hallucinations,
• fever,
• loss of coordination,
• fainting,
• overactive reflexes,
• very stiff (rigid) muscles,
• sweating,
• confusion,
• fast or uneven heartbeats,
• tremors,
• lightheadedness,
• racing thoughts,
• risk-taking behavior,
• decreased inhibitions,
• feelings of extreme happiness or sadness,
• extreme thirst with headache,
• weakness,
• trouble concentrating,
• memory problems,
• confusion,
• seizures (convulsions), or
• shallow breathing.

Trintellix (vortioxetine) tablets are an antidepressant indicated for the treatment of major depressive disorder (MDD).

Viibryd is a prescription medicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of nottreating it. You should discuss all treatment choices with your healthcare provider.

Viibryd is used to treat:

• Major Depressive Disorder (MDD)
• Obsessive Compulsive Disorder (OCD)
• Bulimia Nervosa*
• Panic Disorder*
• Depressive episodes associated with Bipolar I Disorder, taken with olanzapine (Zyprexa)
• Treatment Resistant Depression (depression that has not gotten better with atleast 2 other treatments), taken with olanzapine (Zyprexa)*

*Not approved for use in children

Talk to your healthcare provider if you do not think that your condition is getting betterwith Viibryd treatment.

Trintellix may interact with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans, buspirone, tramadol, tryptophan products, NSAIDs, aspirin, warfarin, bupropion, fluoxetine, paroxetine, quinidine, rifampicin, carbamazepine, and phenytoin. Tell your doctor all medications and supplements you use.

Viibryd is a prescription medicine used to treat a certain type of depression called Major Depressive Disorder (MDD). It is important to talk with your healthcare provider about the risks of treating depression and also the risk of not treating it. You should discuss all treatment choices with your healthcare provider. Talk to your healthcare provider if you do not think that your condition is getting better with Viibryd treatment.

It is not known if Viibryd is safe and effective in children.

The recommended starting dose of Trintellix is 10 mg administered orally once daily without regard to meals. Dosage should then be increased to 20 mg/day, as tolerated.

Take Viibryd exactly as prescribed. Your healthcare provider may need to change the dose of Viibryd until it is the right dose for you.

• Take Viibryd with food. Viibryd may not work as well if you take it on an empty stomach.
• If you miss a dose of Viibryd, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Viibryd at the same time.
• If you take too much Viibryd, call your healthcare provider or poison control center at 1-800-222-1222 right away, or get emergency treatment.