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Qbrexza vs. Botox

Are Qbrexza and Botox the Same Thing?

Qbrexza (glycopyrronium) Cloth and Botox (onabotulinumtoxinA) are used to treat primary axillary hyperhidrosis (sweaty underarms).

Qbrexza Cloth is a topical (on the skin) treatment and Botox is an injectable.

Botox is also used to treat chronic migraines, limb spasticity, cervical dystonia, strabismus, and blepharospasm.

Qbrexza and Botox belong to different drug classes. Qbrexza is an anticholinergic and Botox is an injectable neuro-toxin.

Side effects of Qbrexza and Botox that are similar include dry mouth, headache, and difficulty urinating/urinary hesitancy.

Side effects of Qbrexza that are different from Botox include dilated pupils, mouth pain, sore throat, blurred vision, dry nose, dry throat, dry eye, dry skin, constipation, and local skin reactions (redness, burning/stinging and itching)<./p>

Side effects of Botox that are different from Qbrexza include allergic reactions, rash, itching, neck or back pain, muscle stiffness, difficulty swallowing, shortness of breath, nausea, diarrhea, stomach pain, loss of appetite, muscle weakness, injection site reactions (bruising, bleeding, pain, redness, swelling, or infection), fever, cough, sore throat, runny nose, flu symptoms, cold symptoms, respiratory infections, dizziness, drowsiness, tired feeling, anxiety, ringing in your ears, increased sweating in areas other than the underarms, urinary tract infections (UTIs), and burning/painful urination.

Qbrexza may also interact with other anticholinergic medications.

Botox may also interact with other agents (for example, aminoglycosides, curare) that affect neuromuscular function may increase the effect of botulinum toxin.

What Are Possible Side Effects of Qbrexza?

Common side effects of Qbrexza include:

  • dry mouth,
  • dilated pupils,
  • mouth pain,
  • sore throat,
  • headache,
  • urinary hesitation,
  • blurred vision,
  • dry nose,
  • dry throat,
  • dry eye,
  • dry skin,
  • constipation, and
  • local skin reactions (redness, burning/stinging and itching)

What Are Possible Side Effects of Botox?

Common side effects of Botox include:

  • allergic reactions,
  • rash,
  • itching,
  • headache,
  • neck or back pain,
  • muscle stiffness,
  • difficulty swallowing,
  • shortness of breath,
  • nausea,
  • diarrhea,
  • stomach pain,
  • loss of appetite,
  • muscle weakness,
  • injection site reactions including
    • bruising,
    • bleeding,
    • pain,
    • redness,
    • swelling, or
    • infection,
  • fever,
  • cough,
  • sore throat,
  • runny nose,
  • flu symptoms,
  • cold symptoms
  • respiratory infections,
  • dizziness,
  • drowsiness,
  • tired feeling,
  • anxiety,
  • dry mouth,
  • ringing in your ears,
  • increased sweating in areas other than the underarms,
  • urinary tract infections,
  • burning/painful urination, and
  • difficulty urinating

Drooping of the eyelid (ptosis), inflammation of the cornea (keratitis), eye dryness, itchy eyes, double vision, eye irritation, tearing, increased sensitivity to light, reduced blinking, and eyelid swelling or bruising may occur when used for treating blepharospasm.

What Is Qbrexza?

Qbrexza (glycopyrronium) Cloth is an anticholinergic indicated for topical treatment of primary axillary hyperhidrosis (sweaty underarms) in adults and pediatric patients 9 years of age and older.

What Is Botox?

Botox (onabotulinumtoxinA) is an injectable neuro-toxin used for the treatment of chronic migraines, limb spasticity, axillary hyperhidrosis, cervical dystonia, strabismus, and blepharospasm.

 

What Drugs Interact With Qbrexza?

Qbrexza may interact with other anticholinergic medications. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Qbrexza; it is unknown how it would affect a fetus. It is unknown if Qbrexza passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Botox?

Administration of botulinum toxin with other agents (for example, aminoglycosides, curare) that affect neuromuscular function may increase the effect of botulinum toxin.

 

How Should Qbrexza Be Taken?

Dosage of Qbrexza is a single-use cloth pre-moistened with 2.4% glycopyrronium solution. Qbrexza is for topical use in the underarm area only and not for use in other body areas.

How Should Botox Be Taken?

Botox is administered by injection and dosing depends on the condition that it is used for.