Eucrisa vs. Otezla

• Are Eucrisa and Otezla the Same Thing?
• What Are Possible Side Effects of Eucrisa?
• What Are Possible Side Effects of Otezla?
• What is Eucrisa?
• What is Otezla?
• What Drugs Interact with Eucrisa?
• What Drugs Interact with Otezla?
• How Should Eucrisa Be Taken?
• How Should Otezla Be Taken?

Eucrisa (crisaborole) and Otezla (apremilast) are both phosphodiesterase 4 inhibitors.

Eucrisa is a topical ointment used to treat mild to moderate atopic dermatitis (eczema) in patients 2 years of age and older.

Common side effects of Eucrisa include:

• application site pain

Common side effects of Otezla include:

• diarrhea,
• headache,
• nausea,
• upper respiratory tract infection,
• vomiting,
• runny or stuffy nose,
• abdominal pain,
• fatigue,
• indigestion/heartburn,
• decreased appetite,
• insomnia,
• back pain,
• frequent bowel movements,
• depression,
• bronchitis,
• tooth abscess, and
• sinus headache.

Eucrisa (crisaborole) ointment, 2%, for topical use is a phosphodiesterase 4 inhibitor indicated for topical treatment of mild to moderate atopic dermatitis in patients 2 years of age and older.

Otezla (apremilast) is a phosphodiesterase 4 (PDE4) inhibitor used to treat adult patients with active psoriatic arthritis.

Eucrisa may interact with ther drugs..

Otezla may interact with CYP450 inducers (such as rifampin).

The recommended maintenance dosage is 30 mg twice daily taken orally starting on Day 6, after 5 days of an initial schedule of titration dosing.

The recommended maintenance dosage is 30 mg twice daily taken orally starting on Day 6, after 5 days of an initial schedule of titration dosing.