Emgality vs. Maxalt

Emgality (galcanezumab-gnlm) and Maxalt (rizatriptan) are indicated for the treatment of migraine in adults.

Emgality and Maxalt belong to different drug classes. Emgality is a calcitonin-gene related peptide antagonist and Maxalt is a selective serotonin receptor agonist (a "triptan").

Side effects of Emgality that are different from Maxalt include injection site reactions (such as pain, redness, and itching).

Side effects of Maxalt that are different from Emgality include mild headache (not a migraine), dry mouth, nausea, feeling of pain or tightness in the jaw, neck, or throat; pressure or heavy feeling in any part of your body, dizziness, drowsiness, tired feeling, weakness, feelings of tingling/numbness/prickling/heat, and flushing (warmth, redness, or tingling feeling under your skin).

Emgality may interact with other drugs.

Maxalt may interact with other migraine headache medicines, medicines to treat depression or a psychiatric disorder, narcotics, and medicines to prevent nausea and vomiting.

Common side effects of Emgality include:

• injection site reactions such as pain, redness, and itching

Common side effects of Maxalt include:

• mild headache (not a migraine),
• dry mouth,
• nausea;
• feeling of pain or tightness in the jaw, neck, or throat;
• pressure or heavy feeling in any part of your body,
• dizziness,
• drowsiness,
• tired feeling,
• weakness,
• feelings of tingling/numbness/prickling/heat, or
• flushing (warmth, redness, or tingling feeling under your skin).

Emgality (galcanezumab-gnlm) is a calcitonin-gene related peptide antagonist indicated for the preventive treatment of migraine in adults.

Maxalt (rizatriptan) tablets is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist used to treat the pain of migraine headache. Maxalt is believed to work by narrowing the blood vessels around the brain and by decreasing levels of substances involved in the development of migraine pain. Maxalt will only treat a headache that has already begun. Maxalt will not prevent headaches or reduce the number of attacks.

Emgality may interact with other drugs. Tell your doctor all medications and supplements you use.

Maxalt may interact with other migraine headache medicines, propranolol, or antidepressants. Tell your doctor all medications and supplements you use. It is not known whether this medication is harmful to an unborn baby. Before taking rizatriptan, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is also not known whether rizatriptan passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

The recommended dosage of Emgality is a 240 mg loading dose (administered as two consecutive injections of 120 mg each), followed by monthly doses of 120 mg.

The adult dose of Treximet is 1 mg or 2.5 mg tablets taken with fluid. The dose may be repeated once after 4 hours, for a maximum dose of 5 mg in a 24-hour period.