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Emgality vs. Frova

Are Emgality and Frova the Same Thing?

Emgality (galcanezumab-gnlm) and Frova (frovatriptan succinate) are indicated for the preventive treatment of migraine in adults.

Emgality and Imitrex belong to different drug classes. Emgality is a calcitonin-gene related peptide antagonist and Frova is a selective serotonin receptor agonist (a "triptan").

Side effects of Emgality that are different from Frova include injection site reactions (such as pain, redness, and itching).

Side effects of Frova that are different from Emgality include flushing (warmth, redness, or tingling under the skin), sensations of numbness/prickling/heat under your skin, weakness, stomach upset, dry mouth, drowsiness, dizziness, tired feeling, mild headache (not a migraine), feeling too warm or too cold, bone or joint pain, pressure or heavy feeling in any part of your body, and chest/jaw/neck tightness.

Emgality may interact with other drugs.

Frova may interact with other migraine headache medicines, medicines to treat depression or a psychiatric disorder, medicines for Parkinson's disease, medicines for serious infections, certain herbal products, stimulants, narcotics, and medicines to prevent nausea and vomiting.

What Are Possible Side Effects of Emgality?

Common side effects of Emgality include:

  • injection site reactions such as pain, redness, and itching

What Are Possible Side Effects of Frova?

Common side effects of Frova include:

  • flushing (warmth, redness, or tingling under the skin),
  • sensations of numbness/prickling/heat under your skin,
  • weakness,
  • stomach upset,
  • dry mouth,
  • drowsiness,
  • dizziness,
  • tired feeling,
  • mild headache (not a migraine),
  • feeling too warm or too cold,
  • bone or joint pain,
  • pressure or heavy feeling in any part of your body, or
  • chest/jaw/neck tightness.

What Is Emgality?

Emgality (galcanezumab-gnlm) is a calcitonin-gene related peptide antagonist indicated for the preventive treatment of migraine in adults.

What Is Frova?

Frova (frovatriptan succinate) is a headache medicine used to treat migraine headaches. Frova will only treat a headache that has already begun. Frova will not prevent headaches or reduce the number of attacks.

 

What Drugs Interact With Emgality?

Emgality may interact with other drugs. Tell your doctor all medications and supplements you use.

What Drugs Interact With Frova?

Frova may interact with propranolol or antidepressants. Other drugs may interact with Frova. Tell your doctor all prescription and over-the-counter medications and supplements you use. Frova should be used only when prescribed during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

 

How Should Emgality Be Taken?

The recommended dosage of Emgality is a 240 mg loading dose (administered as two consecutive injections of 120 mg each), followed by monthly doses of 120 mg.

How Should Frova Be Taken?

The recommended dose is a single tablet of Frova taken orally with fluids. If the headache recurs after initial relief, a second tablet may be taken, providing there is an interval of at least 2 hours between doses. The total daily dose of Frova should not exceed 3 tablets (3 x 2.5 mg per day).