Bonsity vs. Reclast

• Are Bonsity and Reclast the Same Thing?
• What Are Possible Side Effects of Bonsity?
• What Are Possible Side Effects of Reclast?
• What Is Bonsity?
• What Is Reclast?
• What Drugs Interact with Bonsity?
• What Drugs Interact with Reclast?
• How Should Bonsity Be Taken?
• How Should Reclast Be Taken?

Bonsity (teriparatide injection) and Reclast (zoledronic acid) are used to treat postmenopausal women with osteoporosis at high risk for fracture; to increase bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture; and for treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture.

Reclast is also used to treat Paget's disease, high blood levels of calcium caused by cancer (hypercalcemia of malignancy, and multiple myeloma (a type of bone marrow cancer) or cancer that has spread from elsewhere in the body to the bone.

Bonsity and Reclast belong to different drug classes. Bonsity is a parathyroid hormone analog (PTH 134) and Reclast is a bisphosphonate.

Side effects of Bonsity and Reclast that are similar include joint pain, nausea, dizziness, headache, diarrhea, constipation, and cough.

Side effects of Bonsity that are different from Reclast include body pain, runny nose, indigestion, and sore throat.

Side effects of Reclast that are different from Bonsity include tiredness, flu-like symptoms (e.g., fever, chills, muscle/joint aches), vision problems, muscle pain, and injection site reactions (pain, redness, swelling).

Bonsity may interact with digoxin.

Reclast may interact with diuretics (water pills), antibiotics, other medicines that can harm your kidneys, cancer medicines, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Common side effects of Bonsity include:

• joint pain,
• body pain,
• nausea,
• runny nose,
• dizziness,
• headache,
• diarrhea,
• constipation,
• indigestion,
• cough, and
• sore throat

Common side effects of Reclast include:

• nausea,
• tiredness,
• flu-like symptoms (e.g., fever, chills, muscle/joint aches),
• cough,
• dizziness,
• headache,
• vision problems,
• diarrhea,
• constipation,
• joint or muscle pain, or
• injection site reactions (pain, redness, swelling).

Bonsity (teriparatide injection) is a parathyroid hormone analog (PTH 1- 34) indicated for treatment of postmenopausal women with osteoporosis at high risk for fracture; to increase bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture; and for treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture.

Reclast is a prescription medicine used to:

• Treat or prevent osteoporosis in women after menopause. Reclast helps reduce the chance of having a hip or spinal fracture (break).
• Increase bone mass in men with osteoporosis.
• Treat or prevent osteoporosis in either men or women who will be taking corticosteroid medicines for at least one year.
• Treat certain men and women who have Paget's disease of the bone.

It is not known how long Reclast works for the treatment and prevention of osteoporosis. You should see your doctor regularly to determine if Reclast is still right for you.

Reclast is not for use in children.

Bonsity may interact with digoxin. Tell your doctor all medications and supplements you use. Bonsity is not recommended for use during pregnancy; it is unknown how it would affect a fetus. It is unknown if Bonsity passes into breast milk. Because of a possible potential for osteosarcoma, breastfeeding is not recommended during treatment with Bonsity.

Reclast may interact with different drugs. Reclast may interact with diuretics (water pills), antibiotics, other medicines that can harm your kidneys, cancer medicines, or nonsteroidal anti-inflammatory drugs (NSAIDs).

The recommended dose of Bonsity is 20 mcg subcutaneously once a day. Bonsity may interact with digoxin.

• Your doctor will tell you how often you will receive Reclast.
• Reclast is given by infusion into your vein (intravenously). Your infusion should last at least 15 minutes.
• Before you receive Reclast, drink at least 2 glasses of fluid (such as water) within a few hours as directed by your doctor.
• You may eat before your treatment with Reclast.
• If you miss a dose of Reclast, call your doctor or healthcare provider to schedule your next dose.