Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

What Is Lyme Disease in Humans?

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Photo of a blacklegged tick, which is a known vector responsible for Lyme disease.
A bacterium called a "spirochete" causes Lyme disease, a tick-borne disease.Source: CDC - James Gathany

Lyme disease in humans facts

  • Lyme disease is an illness that is spread by bites from ticks infected by the bacterium Borrelia burgdorferi, Borrelia mayonii, Borrelia afzelii, or Borrelia garinii.
  • Lyme disease can affect the skin, joints, heart, and nervous system.