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Adcirca Side Effects Center

Medically reviewed by Min Clinic Staff | Updated: January 2026

Adcirca (Tadalafil Tablets) side effects drug center

 

PROFESSIONAL

CONSUMER

SIDE EFFECTS

 

Adcirca Side Effects Center

What Is Adcirca?

Adcirca (tadalafil) is a phosphodiesterase-5 (PDE5) inhibitor used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. The Cialis brand of tadalafil is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate).

What Are Side Effects of Adcirca?

Common side effects of Adcirca include:

  • flushing (redness or warmth in your face, neck, or chest),
  • cold symptoms (such as stuffy nose, sneezing, or sore throat),
  • headache,
  • memory problems,
  • diarrhea or upset stomach, and
  • muscle pain or back pain.

Adcirca may cause serious side effects including:

  • hives, difficulty breathing, or swelling of your face, lips, tongue, or throat;
  • chest pain or pressure, or pain spreading to your jaw or shoulder;
  • shortness of breath;
  • seizures (convulsions);
  • lightheadedness or fainting;
  • sudden vision loss or changes in vision;
  • sudden hearing loss or ringing in your ears;
  • irregular heartbeat; and
  • an erection that is painful or lasts 4 hours or more.

Get medical help right away if you have any of the symptoms listed above.

Dosage for Adcirca

The recommended dose of Adcirca is 40 mg (two 20 mg tablets) taken once daily with or without food.

What Drugs, Substances, or Supplements Interact with Adcirca?

Adcirca may interact with nitrates (used for chest pain), rifabutin, rifampin, rifapentine, antibiotics, antifungals, antidepressants, barbiturates, drugs to treat high blood pressure or a prostate disorder, HIV or AIDS medications, or seizure medications. Tell your doctor all medications and supplements you use.

Adcirca During Pregnancy and Breastfeeding

Adcirca is not expected to harm a fetus. Tell your doctor if you are pregnant or plan to become pregnant. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.