Actisite
- Generic Name: tetracycline periodontal
- Brand Name: Actisite
- Drug Class: Tetracyclines
Actisite (Tetracycline Periodontal) side effects drug center
Actisite Side Effects Center
What Is Actisite?
Actisite (tetracycline hydrochloride) Periodontal Fiber is an antibiotic used as an adjunct to scaling and root planing for reduction of pocket depth and bleeding on probing in patients with adult periodontitis. The brand name Actisite is discontinued, but generic versions may be available.
What Are Side Effects of Actisite?
Common side effects of Actisite (tetracycline hydrochloride) include:
- discomfort on fiber placement and local redness following removal,
- tongue discoloration, sore throat, or
- thrush.
Dosage for Actisite
Actisite fiber provides continuous release dosing of tetracycline for 10 days. At the end of 10 days of treatment, all fibers must be removed.
What Drugs, Substances, or Supplements Interact with Actisite?
Actisite may interact with other drugs. Tell your doctor all medications and supplements you use.
Actisite During Pregnancy or Breastfeeding
During pregnancy, Actisite should be used only if prescribed. This drug passes into breast milk when taken in other forms. It is unknown if it passes into breast milk when used as periodontal fiber. Consult your doctor before breastfeeding.
Additional Information
Our Actisite (tetracycline hydrochloride) Periodontal Fiber Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
Actisite Consumer Information
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severe blistering, peeling, and red skin rash;
- fever, chills, body aches, flu symptoms;
- pale or yellowed skin, easy bruising or bleeding;
- any signs of a new infection.
Common side effects may include:
- nausea, vomiting, diarrhea, upset stomach, loss of appetite;
- white patches or sores inside your mouth or on your lips;
- swollen tongue, black or "hairy" tongue, trouble swallowing;
- sores or swelling in your rectal or genital area; or
- vaginal itching or discharge.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Actisite (Tetracycline Periodontal)
Actisite Professional Information
SIDE EFFECTS
Actisite (tetracycline periodontal) fiber has been studied in 1437 patients distributed as follows over pivotal, controlled, and open- label studies.
| Study Type | ||||
| Demographics | Pivotal | Controlled | Uncontrolled | TOTAL |
| Gender: | ||||
| Male | 113 | 70 | 455 | 638 |
| Female | 113 | 55 | 631 | 799 |
| Age Range | 25-88 | 25-73 | 13-87 | 13-88 |
| Race: | ||||
| Black | 13 | 12 | 41 | 66 |
| Asian | 4 | 1 | 10 | 15 |
| Hispanic | 3 | 3 | 11 | 17 |
| Caucasian | 206 | 105 | 964 | 1275 |
| Native American | 0 | 2 | 56 | 58 |
| Other | 0 | 2 | 5 | 7 |
The most frequently reported adverse reactions in the 226 patients in the pivotal clinical trials were discomfort on fiber placement (10%) and local erythema following removal (11%).
In controlled and open-label trials patients, the following adverse reactions have been reported in less than 1% of patients: oral candidiasis, glossitis, possible allergic response, staining of the tongue, severe gingival inflammation, throbbing pain, pain following placement in an abscessed area, and minor throat irritation.
Read the entire FDA prescribing information for Actisite (Tetracycline Periodontal)
© Actisite Patient Information is supplied by Cerner Multum, Inc. and Actisite Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.