Veregen
Veregen - General Information
Veregen is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis (L.) O Kuntze. Veregen are involved in the clearance of genital and perianal warts.
Pharmacology of Veregen
Veregen is a botanical drug product for topical use. The drug substance in Veregen is Veregen, which is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis O Kuntze, and is a mixture of catechins and other green tea components. Veregen was approved by the FDA in October 2006.
Veregen for patients
Patients using Veregen should receive the following information and instructions:
- This medication is only to be used as directed by a physician. It is for external use only. Eye contact should be avoided as well as application into the vagina or anus.
- It is not necessary to wash off Veregen prior to the next application. When the treatment area is washed or a bath is taken, the ointment should be applied afterwards.
- It is common for patients to experience local skin reactions such as erythema, erosion, edema, itching, and burning at the site of application. Severe skin reactions can occur and should be promptly reported to the healthcare provider. Should severe local skin reaction occur, the ointment should be removed by washing the treatment area with mild soap and water and further doses held.
- Sexual (genital, anal or oral) contact should be avoided while the ointment is on the skin, or the ointment should be washed off prior to these activities. Veregen may weaken condoms and vaginal diaphragms. Therefore the use in combination with Veregen is not recommended.
- Female patients using tampons should insert the tampon before applying the ointment. If the tampon is changed while the ointment is on the skin, accidental application of the ointment into the vagina must be avoided.
- Veregen may stain clothing and bedding.
- Veregen is not a cure and new warts might develop during or after a course of therapy. If new warts develop during the 16–week treatment period, these should also be treated with Veregen.
- The effect of Veregen on the transmission of genital/perianal warts is unknown.
- Patients should be advised to avoid exposure of the genital and perianal area to sun/UV light as Veregen has not been tested under these circumstances.
- The treatment area should not be bandaged or otherwise covered or wrapped as to be occlusive.
- Uncircumcised males treating warts under the foreskin should retract the foreskin and clean the area daily.
Veregen Interactions
Veregen Contraindications
Veregen is contraindicated in individuals with a history of sensitivity reactions to any of the components of the ointment. In case of hypersensitivity, treatment should be discontinued.
Additional information about Veregen
Veregen Indication: For the topical treatment of external genital and perianal warts (Condylomata acuminata) in immunocompetent patients 18 years and older.
Mechanism Of Action: While the exact mechanism of action of catechins is unknown, they are powerful anti-oxidants and are linked to to evidence of fighting tumors as well as enhancing immune system function.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Kunecatechins
Synonyms: Not Available
Drug Category: Not Available
Drug Type: Small Molecule; Nutraceutical; Approved
Other Brand Names containing Kunecatechins: Veregen;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Veregen: Ointment Topical
Chemical IUPAC Name: Not Available
Chemical Formula: Not Available
Kunecatechins on Wikipedia: Not Available
Organisms Affected: Humans and other mammals
