Selexid
Selexid - General Information
Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Pharmacology of Selexid
Selexid is a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.
Additional information about Selexid
Selexid Indication: Used to treat infections due to mecillinam-sensitive organisms such as urinary tract infections, salmonellosis and typhoid fever.
Mechanism Of Action: Selexid interferes with the biosynthesis of the bacterial cell wall however its activity is slightly different from that of other penicillins and cephalosporins
Drug Interactions: Demeclocycline Possible antagonism of action
Doxycycline Possible antagonism of action
Methacycline Possible antagonism of action
Minocycline Possible antagonism of action
Oxytetracycline Possible antagonism of action
Rolitetracycline Possible antagonism of action
Tetracycline Possible antagonism of action
Food Interactions: Not Available
Generic Name: Pivmecillinam
Synonyms: Amdinocillin pivoxil; Pivmecilinamo [inn-spanish]; Pivmecillinamum [inn-latin]
Drug Category: Anti-Bacterial Agents; Anti-Infective Agents, Urinary
Drug Type: Small Molecule; Approved
Other Brand Names containing Pivmecillinam: Coactabs; Selexid;
Absorption: Well absorbed following oral administration.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Selexid: Not Available
Chemical IUPAC Name: 2,2-dimethylpropanoyloxymethyl (5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Chemical Formula: C21H33N3O5S
Pivmecillinam on Wikipedia: Not Available
Organisms Affected: Enteric bacteria and other eubacteria