Rautensin

Rautensin - General Information

A fat-soluble alkaloidal fraction extracted from the root of Rauwolfia serpentina, containing reserpine and other nonadrenolytic amorphous alkaloids; used as a sedative in psychoses, in mild hypertension, and as an adjunct to more potent hypotensive drugs.

Pharmacology of Rautensin

Rautensin is a purified extract of Rauwolfia serpentina, containing reserpine and other amorphous alkaloids. Rautensin is an indole alkaloid antipsychotic and antihypertensive drug known to irreversibly bind to storage vesicles of neurotransmitters such as dopamine, norepinephrine, and serotonin. This leads to depletion of the neurotransmitters and subsequent depression in humans.

Additional information about Rautensin

Rautensin Indication: For the treatment of hypertension and as an adjunct in the management of angina pectoris.
Mechanism Of Action: The antihypertensive actions of alseroxylon are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. Rautensin almost irreversibly blocks the accumulation of noradrenaline and dopamine into synaptic vesicles by inhibiting the Vesicular Monoamine Transporters (VMAT).
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Alseroxylon
Synonyms: Not Available
Drug Category: Adrenergic Uptake Inhibitors
Drug Type: Small Molecule; Approved

Other Brand Names containing Alseroxylon: Rautensin; Rauwiloid;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Rautensin: Tablet Oral
Chemical IUPAC Name: Not Available
Chemical Formula: C33H40N2O9
Alseroxylon on Wikipedia: Not Available
Organisms Affected: Humans and other mammals