Quarzan

Quarzan - General Information

Quarzan is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome.

Pharmacology of Quarzan

Quarzan is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract.

Quarzan for patients

Store in a tight container protected from light. Increase fluids and bulk and exercise to decrease constipation. Do not break, crush, or chew capsules. Avoid alcohol and other CNS depressants and avoid hot environments. It is also recommended to wear sunglasses while outside to prevent photophobia.

Quarzan Interactions

Amantadine, tricyclic antidepressants, and MAOIs may increase anticholinergic effect of clidinium. Clidinium may decrease the effect of phenothiazines, levodopa, and ketoconazole.

Quarzan Contraindications

Hypersensitivity to anticholinergic agents, narrow-angle glaucoma, GI obstruction, myasthenia gravis, paralytic ileus, GI atony, toxic megacolon.

Additional information about Quarzan

Quarzan Indication: For the treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome.
Mechanism Of Action: Inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Clidinium
Synonyms: Not Available
Drug Category: Antiarrhythmic Agents; Anticholinergic Agents; Antispasmodics; Parasympatholytics
Drug Type: Small Molecule; Approved

Other Brand Names containing Clidinium: Quarzan;
Absorption: Not Available
Toxicity (Overdose): Signs of toxicity include confusion, paralytic ileus, urinary hesitancy/retention, and blurred vision.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Quarzan: Not Available
Chemical IUPAC Name: (1-methyl-1-azoniabicyclo[2.2.2]octan-8-yl) 2-hydroxy-2,2-di(phenyl)acetate
Chemical Formula: C22H26NO3+
Clidinium on Wikipedia: https://en.wikipedia.org/wiki/Clidinium
Organisms Affected: Humans and other mammals