Propethonum

Propethonum - General Information

Propethonum is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Propethonum is an antimuscarinic, anticholinergic drug.

Pharmacology of Propethonum

Propethonum is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Propethonum is an antimuscarinic, anticholinergic drug.

Additional information about Propethonum

Propethonum Indication: Used as an adjunct in the treatment of peptic ulcer disease
Mechanism Of Action: Propethonum binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Propethonum inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Tridihexethyl
Synonyms: Not Available
Drug Category: Antispasmodics; Anticholinergic Agents
Drug Type: Small Molecule; Approved

Other Brand Names containing Tridihexethyl: Pathilon; Propethonum;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Propethonum: Not Available
Chemical IUPAC Name: (3-cyclohexyl-3-hydroxy-3-phenylpropyl)-triethylazanium
Chemical Formula: C21H36NO+
Tridihexethyl on Wikipedia: Not Available
Organisms Affected: Humans and other mammals