Propanthel

Propanthel - General Information

A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking. [PubChem]

Pharmacology of Propanthel

Propanthel is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscle. Propanthel is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Propanthel inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions.

Additional information about Propanthel

Propanthel Indication: For the treatment of enuresis.
Mechanism Of Action: Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic).
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Propantheline
Synonyms: Propantheline Bromide; Propanthelinium; Propanthelinum
Drug Category: Anti-Ulcer Agents; Antimuscarinics; Antispasmodics; Muscarinic Antagonists
Drug Type: Small Molecule; Approved

Other Brand Names containing Propantheline: Pro-Banthine; Propanthel;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Propanthel: Tablet Oral
Chemical IUPAC Name: methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium
Chemical Formula: C23H30NO3+
Propantheline on Wikipedia: https://en.wikipedia.org/wiki/Propantheline
Organisms Affected: Humans and other mammals