Propanthel: Full Drug Profile
Propanthel - General Information
A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking. [PubChem]
Pharmacology of Propanthel
Propanthel is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscle. Propanthel is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Propanthel inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions.
Additional information about Propanthel
Propanthel Indication: For the treatment of enuresis. Mechanism Of Action: Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic). Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Propantheline Synonyms: Propantheline Bromide; Propanthelinium; Propanthelinum Drug Category: Anti-Ulcer Agents; Antimuscarinics; Antispasmodics; Muscarinic Antagonists Drug Type: Small Molecule; Approved Other Brand Names containing Propantheline: Pro-Banthine; Propanthel; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Propanthel: Tablet Oral Chemical IUPAC Name: methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium Chemical Formula: C23H30NO3+ Propantheline on Wikipedia: https://en.wikipedia.org/wiki/Propantheline Organisms Affected: Humans and other mammals