Praticef: Full Drug Profile

Praticef - General Information

A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections. [PubChem]

Pharmacology of Praticef

Praticef is a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

Additional information about Praticef

Praticef Indication

For the treatment of bacterial infections caused by susceptible microorganisms.

Mechanism Of Action

Praticef, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.

Generic Name

Cefonicid

Synonyms

Cefonicido [inn-spanish]; Cefonicidum [inn-latin]

Drug Category

Cephalosporins; Antibacterial Agents

Drug Type

Small Molecule; Approved

Other Brand Names containing Cefonicid

Monocid; Praticef;

Protein Binding

98% bound to plasma proteins.

Biotransformation

Not metabolized.

Half Life

4.5 hours

Dosage Forms of Praticef

Solution Intramuscular

Chemical IUPAC Name

(6R,7R)-7-[(2-hydroxy-2-phenylacetyl)amino]-8-oxo-3-[[1-(sulfomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Chemical Formula

C18H18N6O8S3

Organisms Affected

Enteric bacteria and other eubacteria