Praticef
Praticef - General Information
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections. [PubChem]
Pharmacology of Praticef
Praticef is a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Additional information about Praticef
Praticef Indication: For the treatment of bacterial infections caused by susceptible microorganisms.
Mechanism Of Action: Praticef, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Cefonicid
Synonyms: Cefonicido [inn-spanish]; Cefonicidum [inn-latin]
Drug Category: Cephalosporins; Antibacterial Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Cefonicid: Monocid; Praticef;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: 98% bound to plasma proteins.
Biotransformation: Not metabolized.
Half Life: 4.5 hours
Dosage Forms of Praticef: Solution Intramuscular
Solution Intravenous
Chemical IUPAC Name: (6R,7R)-7-[(2-hydroxy-2-phenylacetyl)amino]-8-oxo-3-[[1-(sulfomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Chemical Formula: C18H18N6O8S3
Cefonicid on Wikipedia: Not Available
Organisms Affected: Enteric bacteria and other eubacteria