Phenylazo

Phenylazo - General Information

A local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity. [PubChem]

Pharmacology of Phenylazo

Phenylazo is a local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.

Phenylazo for patients

Patients should be informed that Phenazopyridine HCl produces a reddish-orange discoloration of the urine and may stain fabric. Staining of contact lenses has been reported.

Phenylazo Interactions

Phenylazo Contraindications

Phenazopyridine HCl should not be used in patients who have previously exhibited hypersensitivity to it. The use of Phenazopyridine HCl is contraindicated in patients with renal insufficiency.

Additional information about Phenylazo

Phenylazo Indication: For the symptomatic relief of pain, burning, urgency, frequency, and other discomforts arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters.
Mechanism Of Action: Phenylazo's mechanism of action is not well known, and only basic information on its interaction with the body is available. It is known that the chemical has a direct topical analgesic effect on the mucosa lining of the urinary tract.
Drug Interactions: Not Available
Food Interactions: Take with food.
Generic Name: Phenazopyridine
Synonyms: Pyridacil; PAP; PDP
Drug Category: Anesthetics, Local
Drug Type: Small Molecule; Approved

Other Brand Names containing Phenazopyridine: Azo-Standard; Baridium; Phenazodine; Prodium; Pyridiate; Pyridium; Sedural; Uristat; Urodine; Urogesic; Suladyne; Viridium; Pyrazodine; Phenylazo;
Absorption: Not Available
Toxicity (Overdose): Methemoglobinemia generally follows a massive, acute overdose.
Protein Binding: Not Available
Biotransformation: Likely hepatic but also in other tissues. One of the metabolites is acetaminophen.
Half Life: Not Available
Dosage Forms of Phenylazo: Tablet Oral
Tablet Oral
Chemical IUPAC Name: 3-phenyldiazenylpyridine-2,6-diamine
Chemical Formula: C11H11N5
Phenazopyridine on Wikipedia: https://en.wikipedia.org/wiki/Phenazopyridine
Organisms Affected: Humans and other mammals