Pathilon: Full Drug Profile

Pathilon - General Information

Pathilon is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Pathilon is an antimuscarinic, anticholinergic drug.

Pharmacology of Pathilon

Pathilon is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Pathilon is an antimuscarinic, anticholinergic drug.

Additional information about Pathilon

Pathilon Indication

Used as an adjunct in the treatment of peptic ulcer disease

Mechanism Of Action

Pathilon binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Pathilon inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach.

Generic Name

Tridihexethyl

Drug Category

Antispasmodics; Anticholinergic Agents

Drug Type

Small Molecule; Approved

Other Brand Names containing Tridihexethyl

Pathilon; Propethonum;

Chemical IUPAC Name

(3-cyclohexyl-3-hydroxy-3-phenylpropyl)-triethylazanium

Chemical Formula

C21H36NO+

Organisms Affected

Humans and other mammals