Pagitane
Pagitane - General Information
Pagitane is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.
Pharmacology of Pagitane
Pagitane is a central anticholenergic used in the treatment of the symptoms of Parkinson's disease. It is a drug used to reduce levels of acetylcholine. Acetylcholine is usually in balance with dopamine neurotransmitters, however lower levels of dopamine are present in the brain of patients suffering from Parkinson's disease. By lowering levels of acetylcholine, it is thought that this balance may be restored.
Additional information about Pagitane
Pagitane Indication: For treatment and management of Parkinson's disease.
Mechanism Of Action: Pagitane binds the muscarinic acetylcholine receptor M1, effectively inhibiting acetylcholine. This decrease in acetylcholine restores the normal dopamine-acetylcholine balance and relieves the symptoms of Parkinson's disease.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Cycrimine
Synonyms: Cycrimine hydrochloride
Drug Category: Antiparkinson Agents; Antidyskinetics
Drug Type: Small Molecule; Approved
Other Brand Names containing Cycrimine: Pagitane;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: 14-21%
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Pagitane: Not Available
Chemical IUPAC Name: 1-cyclopentyl-1-phenyl-3-piperidin-1-ylpropan-1-ol
Chemical Formula: C19H29NO
Cycrimine on Wikipedia: Not Available
Organisms Affected: Humans and other mammals