Pagitane: Full Drug Profile

Pagitane - General Information

Pagitane is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.

Pharmacology of Pagitane

Pagitane is a central anticholenergic used in the treatment of the symptoms of Parkinson's disease. It is a drug used to reduce levels of acetylcholine. Acetylcholine is usually in balance with dopamine neurotransmitters, however lower levels of dopamine are present in the brain of patients suffering from Parkinson's disease. By lowering levels of acetylcholine, it is thought that this balance may be restored.

Additional information about Pagitane

Pagitane Indication

For treatment and management of Parkinson's disease.

Mechanism Of Action

Pagitane binds the muscarinic acetylcholine receptor M1, effectively inhibiting acetylcholine. This decrease in acetylcholine restores the normal dopamine-acetylcholine balance and relieves the symptoms of Parkinson's disease.

Generic Name

Cycrimine

Synonyms

Cycrimine hydrochloride

Drug Category

Antiparkinson Agents; Antidyskinetics

Drug Type

Small Molecule; Approved

Other Brand Names containing Cycrimine

Pagitane;

Protein Binding

14-21%

Chemical IUPAC Name

1-cyclopentyl-1-phenyl-3-piperidin-1-ylpropan-1-ol

Chemical Formula

C19H29NO

Organisms Affected

Humans and other mammals